DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30184 and TRRAP

DIOPT Version :9

Sequence 1:	NP_726341.1	Gene:	CG30184 / 246506	FlyBaseID:	FBgn0050184	Length:	223	Species:	Drosophila melanogaster
Sequence 2:	NP_001362453.1	Gene:	TRRAP / 8295	HGNCID:	12347	Length:	3873	Species:	Homo sapiens

Alignment Length:	108	Identity:	30/108 - (27%)
Similarity:	39/108 - (36%)	Gaps:	24/108 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 LEEFRTERWPSFYA-CCRDNAIVALYAGAIYLMH--CTFALD----LMFSHSRSRANQKMHPQRS 153
            |....|..||...: .|.|.|  ..|:|.:.|.|  ..||:.    |...||..:|    |...:
Human  1865 LRRLMTFAWPCLLSKACVDPA--CKYSGHLLLAHIIAKFAIHKKIVLQVFHSLLKA----HAMEA 1923

  Fly   154 KRPLQLYFISRGAEAYLSRFWFFRRIAARMLTSAQPSEHSGRK 196
            :.      |.|.|.|.|:     ..:.|||....|...|..||
Human  1924 RA------IVRQAMAILT-----PAVPARMEDGHQMLTHWTRK 1955

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
CG30184	NP_726341.1	None
TRRAP	NP_001362453.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	491..541
		Interaction with TP53. /evidence=ECO:0000269\|PubMed:12138177	2017..2395
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2030..2051
		Bipartite nuclear localization signal. /evidence=ECO:0000255	2054..2069
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2550..2585
		TEL1	<2552..3873	CDD:227365
		FAT	2868..3200	CDD:367004
		PIKK_TRRAP	3510..3797	CDD:270707
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900