DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30184 and pik3c2a

DIOPT Version :9

Sequence 1:	NP_726341.1	Gene:	CG30184 / 246506	FlyBaseID:	FBgn0050184	Length:	223	Species:	Drosophila melanogaster
Sequence 2:	XP_005159362.2	Gene:	pik3c2a / 571356	ZFINID:	ZDB-GENE-030328-39	Length:	1691	Species:	Danio rerio

Alignment Length:	235	Identity:	43/235 - (18%)
Similarity:	79/235 - (33%)	Gaps:	77/235 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 GCCLVHWTCFMEEGVPHIFLLCGTYGGSVIICFISLIGAFYAERPT--MKHEALFGGILGGLHMV 85
            |||:          ..:|..:|..:..::::            |.|  |.| ..||..||...|:
Zfish  1240 GCCV----------ATYILGICDRHNDNIML------------RSTGHMFH-IDFGKFLGHAQMI 1281

  Fly    86 TVYANMYVATLEEFRTERWPSFYACCRDNAIVALYAG-------AIYLMHCTFALDLMFSHSRSR 143
                       ..|:.:|.|  :....|.|.| :..|       .:::..|:.|.:|:..||...
Zfish  1282 -----------GSFKRDRAP--FVLTSDMAYV-INGGERPTSRFQLFVDLCSQAYNLIRKHSNLF 1332

  Fly   144 AN-----------------------QKMHPQRSKRPLQLYF---ISRGAEAYLSRFWFFRRIAAR 182
            .|                       ..:.||.:.....::|   |.....:..::|.||....|:
Zfish  1333 LNLLSLMTQSGLPELTGVQDLKYVYDALQPQTTDAEATIFFTRLIESSLGSVATKFNFFIHNLAQ 1397

  Fly   183 MLTSAQPSEHSGRKRQVSSSESDSDAKEREEERIRNSEVF 222
            :..|..||..     :...|.:......:::.:||::.||
Zfish  1398 LRFSGLPSND-----EPILSFAPRTYTMKQDGKIRDASVF 1432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30184	NP_726341.1	None
pik3c2a	XP_005159362.2	Amelogenin	<137..207	CDD:330537
		PI3K_rbd	420..507	CDD:307097
		C2A_PI3K_class_II	681..852	CDD:175979
		PI3Ka	872..1038	CDD:320871
		PKc_like	1045..1397	CDD:328722	34/193 (18%)
		PX_PI3K_C2_alpha	1428..1536	CDD:132822	2/5 (40%)
		C2B_PI3K_class_II	1565..1686	CDD:176027
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900