DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG30184 and Mtor

DIOPT Version :9

Sequence 1:NP_726341.1 Gene:CG30184 / 246506 FlyBaseID:FBgn0050184 Length:223 Species:Drosophila melanogaster
Sequence 2:NP_063971.1 Gene:Mtor / 56718 RGDID:68371 Length:2549 Species:Rattus norvegicus


Alignment Length:131 Identity:29/131 - (22%)
Similarity:52/131 - (39%) Gaps:26/131 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    85 VTVYANMYVATLEEFRTERWPSFYACCRDNAIVALYAGAIYLMHCTFALDLMFSHSRSRANQKMH 149
            :.:..::.|:..|:.||  |..:.:.|..       :|.:.|.|.|..|.|....||    |..|
  Rat  1636 ILMVRSLVVSPHEDMRT--WLKYASLCGK-------SGRLALAHKTLVLLLGVDPSR----QLDH 1687

  Fly   150 PQRSKRPLQLYFISRGAEAYLSRFWFFRRIAARMLTSAQPSEH--SGRKRQVSSSESDSDAKERE 212
            |..:..|...|       ||:...|    .:||.:.:.|..:|  ...::|...:.:..|.:.::
  Rat  1688 PLPTVHPQVTY-------AYMKNMW----KSARKIDAFQHMQHFVQTMQQQAQHAIATEDQQHKQ 1741

  Fly   213 E 213
            |
  Rat  1742 E 1742

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG30184NP_726341.1 None
MtorNP_063971.1 HEAT repeat 993..1021 CDD:293787
HEAT 25 1029..1068
HEAT repeat 1033..1062 CDD:293787
HEAT 26 1069..1105
HEAT repeat 1073..1099 CDD:293787
HEAT 27 1106..1144
HEAT repeat 1111..1142 CDD:293787
HEAT 28 1145..1188
HEAT repeat 1154..1180 CDD:293787
HEAT 29 1189..1225
HEAT 30 1226..1273
HEAT 31 1274..1311
HEAT 32 1312..1345
TPR 1 1346..1382
TPR 2 1383..1408
TPR 3 1409..1442
TPR 4 1443..1473
TPR 5 1474..1507
TPR 6 1508..1541
TPR 7 1542..1574
TPR 8 1575..1614
TPR 9 1615..1649 1/12 (8%)
TPR 10 1650..1693 15/55 (27%)
TPR 11 1694..1731 10/47 (21%)
TPR 12 1732..1786 2/11 (18%)
TPR 13 1787..1846
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1812..1867
TPR 14 1898..1930
TPR 15 1931..1970
TPR 16 1971..2005
Sufficient for interaction with the FKBP1A/rapamycin complex. /evidence=ECO:0000250 2012..2144
Rapamycin_bind 2015..2112 CDD:285924
PIKKc_TOR 2153..2431 CDD:270713
Interaction with MLST8. /evidence=ECO:0000250 2258..2296
FATC 2518..2549 CDD:280430
Interaction with NBN. /evidence=ECO:0000250 1..651
TEL1 363..2549 CDD:227365 29/131 (22%)
HEAT 16 637..683
HEAT repeat 655..681 CDD:293787
HEAT 17 686..724
HEAT repeat 691..721 CDD:293787
HEAT 18 727..766
HEAT repeat 729..759 CDD:293787
HEAT 19 769..811
HEAT repeat 772..805 CDD:293787
HEAT 20 814..853
HEAT repeat 817..847 CDD:293787
DUF3385 854..1024 CDD:288698
HEAT 21 857..893
HEAT 22 894..942
HEAT 23 943..988
HEAT repeat 955..981 CDD:293787
HEAT 24 989..1027
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5032
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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