DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30184 and pik3cd

DIOPT Version :9

Sequence 1:	NP_726341.1	Gene:	CG30184 / 246506	FlyBaseID:	FBgn0050184	Length:	223	Species:	Drosophila melanogaster
Sequence 2:	NP_957493.1	Gene:	pik3cd / 394174	ZFINID:	ZDB-GENE-040426-1128	Length:	1039	Species:	Danio rerio

Alignment Length:	120	Identity:	23/120 - (19%)
Similarity:	47/120 - (39%)	Gaps:	26/120 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 MEEGVPHIFLLCGTYGGSVIICFISLIGAFYAERPTMKHEAL-----FGGILG------GLH--- 83
            :::.:....|.|..|   .:..::..||..:::...::....     ||..||      |::
Zfish   864 LDQAIEEFTLSCAGY---CVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKSKFGINRER 925

  Fly    84 --MVTVYANMYVATLEEFRT---ERWPSFYACCRDNAIVALYAGAIYLMHCTFAL 133
              .:..|.  :|..::|.||   |::..|..||.....:....|.:::.  .|||
Zfish   926 VPFILTYD--FVHVIQEGRTNNSEKFERFRVCCEQAYKILCRNGTLFVN--LFAL 976

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30184	NP_726341.1	None
pik3cd	NP_957493.1	PI3K_p85B	32..107	CDD:280372
		PI3K_rbd	188..280	CDD:295323
		C2_PI3K_class_I_beta_delta	315..481	CDD:176075
		PI3Ka_I	505..676	CDD:238444
		PI3Kc_IA_delta	676..1038	CDD:270718	23/120 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900