DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30184 and Pik3c2b

DIOPT Version :9

Sequence 1:	NP_726341.1	Gene:	CG30184 / 246506	FlyBaseID:	FBgn0050184	Length:	223	Species:	Drosophila melanogaster
Sequence 2:	NP_001092746.2	Gene:	Pik3c2b / 240752	MGIID:	2685045	Length:	1632	Species:	Mus musculus

Alignment Length:	205	Identity:	42/205 - (20%)
Similarity:	69/205 - (33%)	Gaps:	45/205 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 GCCLVHWTCFMEEGVPHIFLLCGTYGGSVII-----CFISLIGAFYAERPTMKHEALFGGILGGL 82
            |||:          ..:|..:|..:..::::     .|....|.|      :.|..:||.|....
Mouse  1182 GCCV----------ATYILGICDRHNDNIMLKTTGHMFHIDFGRF------LGHAQMFGNIKRDR 1230

  Fly    83 HMVTVYANM-YVATLEEFRTERWPSFY-ACCRDNAIVA----LYAGAIYLMHCTFALDLMFSHSR 141
            ......::| ||....:..:.|:..|. .||:...::.    |:...:.||......:|......
Mouse  1231 APFVFTSDMAYVINGGDKPSSRFHDFVDLCCQAYNLIRKHTHLFLNLLGLMLSCGIPELSDLEDL 1295

  Fly   142 SRANQKMHPQRSKRPLQLYFI-----SRGAEAYLSRFWFFRRIAA--------RMLTSAQPSEH- 192
            ......:.||.::.....||.     |.|:.|....| |...:|.        |:..|..|..|
Mouse  1296 KYVYDALRPQDTEANATTYFTRLIESSLGSVATKLNF-FIHNLAQMKFTGSDDRLTLSFAPRTHT 1359

  Fly   193 ---SGRKRQV 199
               |||.|.|
Mouse  1360 LKSSGRIRDV 1369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30184	NP_726341.1	None
Pik3c2b	NP_001092746.2	PI3K_rbd	363..465	CDD:366310
		C2A_PI3K_class_II	621..793	CDD:175979
		PI3Ka_II	812..980	CDD:238441
		PI3Kc_C2_beta	986..1339	CDD:119421	32/173 (18%)
		PX_PI3K_C2_beta	1368..1476	CDD:132823	1/2 (50%)
		C2B_PI3K_class_II	1504..1626	CDD:176027
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900