DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk3 and ppk24

DIOPT Version :9

Sequence 1:	NP_726336.1	Gene:	ppk3 / 246504	FlyBaseID:	FBgn0050181	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_651860.2	Gene:	ppk24 / 43702	FlyBaseID:	FBgn0039839	Length:	595	Species:	Drosophila melanogaster

Alignment Length:	534	Identity:	105/534 - (19%)
Similarity:	172/534 - (32%)	Gaps:	160/534 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 LCVNRSIH-----------LLERLFWLA--VVVSSVIAALVLSRLQLERYFSSPTVISVDRDYRG 108
            |..|.|.|           :.||.||..  :...:|:.|.:......|:.....|:  ....|..
  Fly    64 LLQNLSFHCYSKLVESGRRIQERFFWFVFHITALTVLIAFLWGTYTKEQEALVTTM--YHPMYPI 126

  Fly   109 WNGSLPAVTLCYYDHIDSFKANEYIQEMWNVSIIDEDYFYFMD----FLYAVVNAT----AGNYA 165
            |....||:::|..:.|....|.:|...:........:..:|.|    |:|...:.:    ..|..
  Fly   127 WKVEFPAISVCSLNRISQRAAWQYAHNLSGKDPKQRNASHFYDQLKAFMYMYYDPSDLMDIDNAL 191

  Fly   166 ELAKFAEDERFDQI--------------------DLYEMIQRVDRPFEQVISSFDAGFQVHVQRV 210
            ....|.  :|||..                    |::...:...|.|: .:..|:.        .
  Fly   192 RFQSFL--DRFDTAKEELFFNTRNRMSALTPNCSDMFVSCRIAGRLFD-CMDKFET--------T 245

  Fly   211 MTERGACYAIN-----------------SPMSTVLSGQPVAYELMPQPLSCQYGKQQCYIRMDLY 258
            :|..|.|...|                 ..|..||:       |...|..            :.|
  Fly   246 LTSHGFCCTFNYDGRYVNKRDFRQRYFGPDMGLVLT-------LKTDPSD------------NFY 291

  Fly   259 ESTGVLDVHSPF------EVSATEANIVALHKSDEITASFKVLETVASKNLRQLSVAQRKCVFNN 317
            :..|......||      .|:.|..|.:       :....|:.||:  ...|.:|.:.|||:|.|
  Fly   292 KINGHNGYPDPFSGGVAERVAETGFNTL-------LPVRAKIFETL--PEARSMSPSVRKCLFEN 347

  Fly   318 E-ETSNLKIYSKSLCLARCRAVMALEMCNCVPFFYP--YVDGPS----CNPAGFECL--LDFKWP 373
            | .....:.|:.|.|::.|||...:.:|.||||..|  |:||..    |......||  .:|||.
  Fly   348 EMPWIFARHYTFSKCISACRAQSVVSLCECVPFSLPHRYIDGSEKRIYCTLQHLACLKRYEFKWL 412

  Fly   374 IW----------------ALHICKCPSTCTEIEY-----------TMQTVK-----------KSS 400
            ..                ||:...|.::|||..|           |...:|           .:|
  Fly   413 NVITSRENVTGLEHELQDALYCPLCLASCTETRYSVRGAMTLGLPTPSQIKGPARSNPGPRANNS 477

  Fly   401 WGVKNNEEVASSETATSSFRWDLIPPKVRMRRDVVYSFEDLVVS--------FGGVLALFVGVSV 457
            :|..::...|.....:||...:|...::......:..|..::.|        .|.:..:..|.|:
  Fly   478 YGPASSSGSAKGPVHSSSAPAELAVVRIYFAETHIQYFRQIIKSAWYETFSTIGNICGIIAGFSL 542

  Fly   458 MGLVEMVHVLVNNL 471
            :|:.|::..|...|
  Fly   543 IGICELLFFLAKQL 556

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk3	NP_726336.1	ASC	59..464	CDD:279230	102/523 (20%)
ppk24	NP_651860.2	ASC	65..551	CDD:279230	102/526 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920