Protein Alignment ppk3 and Scnn1a

DIOPT Version :9

• Sequence 1: NP_726336.1
• Gene: ppk3 / 246504
• FlyBaseID: FBgn0050181
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_035454.2
• Gene: Scnn1a / 20276
• MGIID: 101782
• Length: 700
• Species: Mus musculus
• Alignment Length: 587
• Identity: 110/587 - (18%)
• Similarity: 184/587 - (31%)
• Gaps: 208/587 - (35%)

  Fly    58 CVNRSIHLLERL-----------FWLAVVVSSVIAALVLSRLQLERYFSSPTVISVDRDYRGWNG 111
            |.|.:||...||           ||..:.:.:.........|..|.|||.|..::::     .|.
Mouse    89 CNNTTIHGAIRLVCSKHNRMKTAFWAVLWLCTFGMMYWQFALLFEEYFSYPVSLNIN-----LNS 148

  Fly   112 S---LPAVTLCYYDHIDSFKANEYIQEMWNVSIIDEDYFYFMDFLYAVVNATAG----------- 162
            .   .||||:|   .::.::..|..:::..:..|.|...:.:....:.....||
Mouse   149 DKLVFPAVTVC---TLNPYRYTEIKEDLEELDRITEQTLFDLYKYNSSYTRQAGGRRRSTRDLRG 210

  Fly   163 ---------------NYAELAKFAEDERFD---QIDL------YEMI-QRVDRPFEQVISS-FDA 201
                           |.|..|:.|.....|   |:|.      :::. |.....|.|..|| .||
Mouse   211 ALPHPLQRLRTPPPPNPARSARSASSSVRDNNPQVDRKDWKIGFQLCNQNKSDCFYQTYSSGVDA 275

  Fly   202 ---GFQVHVQRVMTE---------------------------------------RGACYAINSPM 224
               .::.|...:::.                                       .|.||..|:..
Mouse   276 VREWYRFHYINILSRLPDTSPALEEEALGSFIFTCRFNQAPCNQANYSQFHHPMYGNCYTFNNKN 340

  Fly   225 STVL--SGQPVAYELMPQPLSCQYGKQQCYIRMDLYESTGVLDVHSPFEVSATEANIVALHKSDE 287
            ::.|  |..|.....:...|..:   |..:|               |...:.|.|.:: :|..||
Mouse   341 NSNLWMSSMPGVNNGLSLTLRTE---QNDFI---------------PLLSTVTGARVM-VHGQDE 386

  Fly   288 IT----ASFKVLETVASKNLRQLSVAQRK------------CVFNNEE--TSNL--KIYSKSLCL 332
            ..    ..|.|...|      :.|::.||            |..|..:  ..||  ..|::.:|:
Mouse   387 PAFMDDGGFNVRPGV------ETSISMRKEALDSLGGNYGDCTENGSDVPVKNLYPSKYTQQVCI 445

  Fly   333 ARCRAVMALEMCNCVPFFYPYVDGPSCNPAGFECLLDFKWPIWALHIC----------------- 380
            ..|.....::.|.|...|||       .|.|.|.....|...|.  .|
Mouse   446 HSCFQENMIKKCGCAYIFYP-------KPKGVEFCDYLKQSSWG--YCYYKLQAAFSLDSLGCFS 501

  Fly   381 KCPSTCTEIEYTMQ-------TVKKSSW-----GVKNNEEVASSETATS---------SFRWDLI 424
            ||...|:...|.:.       :||...|     .::||..:.:.....:         :::.:..
Mouse   502 KCRKPCSVTNYKLSAGYSRWPSVKSQDWIFEMLSLQNNYTINNKRNGVAKLNIFFKELNYKTNSE 566

  Fly   425 PPKVRMRRDVVYSFEDLVVSFGGVLALFVGVSVMGLVEMVHVLVNNLLLDVFTLLRLMLGRLR-R 488
            .|.|.|        ..|:.:.|...:|:.|.||:.:|||..::.:.|   |.||: ::|.|.| |
Mouse   567 SPSVTM--------VSLLSNLGSQWSLWFGSSVLSVVEMAELIFDLL---VITLI-MLLHRFRSR 619

  Fly   489 CW 490
            .|
Mouse   620 YW 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk3	NP_726336.1	ASC	59..464	CDD:279230	99/557 (18%)
Scnn1a	NP_035454.2	ENaC	80..677	CDD:273304	110/587 (19%)
		deg-1	88..600	CDD:273309	101/560 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820