Protein Alignment ppk3 and Asic1

DIOPT Version :10

• Sequence 1: NP_726336.1
• Gene: ppk3 / 246504
• FlyBaseID: FBgn0050181
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_001276720.1
• Gene: Asic1 / 11419
• MGIID: 1194915
• Length: 559
• Species: Mus musculus
• Alignment Length: 504
• Identity: 103/504 - (20%)
• Similarity: 155/504 - (30%)
• Gaps: 160/504 - (31%)

  Fly    40 RDVVAQAGAETGLLALSLCVNRSIHLL-------ERLFWLAVVVSSVIAALVLSRLQLERYFSSP 97
            ||:||        .|.|..::.:.|:.       .:..|....|.::.|.|.....::..|.|.|
Mouse    61 RDLVA--------FANSCTLHGASHVFVEGGPGPRQALWAVAFVIALGAFLCQVGDRVAYYLSYP 117

  Fly    98 TVISVDRDYRGWNGSLPAVTLCYYDHIDSFKANEYIQEMWNVSIIDEDYFYFMDFLY-------- 154
            .|..:| :........||||.|                  |.:.:......:.|.||
Mouse   118 HVTLLD-EVATTELVFPAVTFC------------------NTNAVRLSQLSYPDLLYLAPMLGLD 163

  Fly   155 -----AVVNATAGNYAELAKFAEDERF--DQIDLYEMIQRVDRPFEQVI--SSFDAG------FQ 204
                 .|..|..|          .|.|  :..:|:....|.....|.::  .|:..|      |.
Mouse   164 ESDDPGVPLAPPG----------PEAFSGEPFNLHRFYNRSCHRLEDMLLYCSYCGGPCGPHNFS 218

  Fly   205 VHVQRVMTERGACYAINS------PMSTVLSGQPVAYELMPQPLSCQYGKQQCYIRMDLYESTGV 263
            |    |.|..|.||..||      .:.|:..|.....|:|..            |:.|.|
Mouse   219 V----VFTRYGKCYTFNSGQDGRPRLKTMKGGTGNGLEIMLD------------IQQDEY----- 262

  Fly   264 LDVHSPFEVSATEANI-VALHKSDE----------ITASFKVLETVASKNLRQLSVAQRKCVFNN 317
            |.|....:.::.||.| |.:|..||          :...|:...:...:.|..|......|....
Mouse   263 LPVWGETDETSFEAGIKVQIHSQDEPPFIDQLGFGVAPGFQTFVSCQEQRLIYLPSPWGTCNAVT 327

  Fly   318 EETSNLKIYSKSLCLARCRAVMALEMCNCVPFFYPYVDGPSCNPAGF-EC---LLDFKWPIWAL- 377
            .::.....||.:.|...|.....:|.|||.....| .|.|.|.|..: ||   .|||      |
Mouse   328 MDSDFFDSYSITACRIDCETRYLVENCNCRMVHMP-GDAPYCTPEQYKECADPALDF------LV 385

  Fly   378 ----HICKCPSTC-----------------TEIEYTMQTVKKSSWGVKNN-------EEVASSET 414
                ..|.|...|                 ...:|..:...||...:..|       .||.:.||
Mouse   386 EKDQEYCVCEMPCNLTRYGKELSMVKIPSKASAKYLAKKFNKSEQYIGENILVLDIFFEVLNYET 450

  Fly   415 ATSSFRWDLIPPKVRMRRDVVYSFEDLVVSFGGVLALFVGVSVMGLVEM 463
                           :.:...|....|:...||.:.||:|.|::.::|:
Mouse   451 ---------------IEQKKAYEIAGLLGDIGGQMGLFIGASILTVLEL 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk3	NP_726336.1	ASC	59..464	CDD:459966	97/485 (20%)
Asic1	NP_001276720.1	ENaC	63..541	CDD:273304	101/502 (20%)