DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30178 and FHL5

DIOPT Version :9

Sequence 1:	NP_726395.1	Gene:	CG30178 / 246501	FlyBaseID:	FBgn0050178	Length:	187	Species:	Drosophila melanogaster
Sequence 2:	NP_001164278.1	Gene:	FHL5 / 9457	HGNCID:	17371	Length:	284	Species:	Homo sapiens

Alignment Length:	178	Identity:	47/178 - (26%)
Similarity:	79/178 - (44%)	Gaps:	6/178 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ASICCRCNEKIWP--RAVCSLGKTYHPHHFTCKECGLVVDPKLFFAVDDDVVCSECYLDKHAARC 65
            :|.|..|...|.|  |.:...|..:|...|.|:.|...:..|...:.:....|..|:..:.|..|
Human    99 SSKCFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYC 163

  Fly    66 SACRTPILERGVAAAERKWHEKCFRCVSCSKSLVSASFFEVNGYLFCKAHFRELFSSRCAGCEKP 130
            :.|:..|...|:...::.||::||.|..|.|.|....|...:.|.||...:..|::::|..|.||
Human   164 NFCKKVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYPFCVDCYNHLYANKCVACSKP 228

  Fly   131 ID----RRAVVALSTKWHAKCFKCHHCRKRISAREFWIENGQPICAAC 174
            |.    .:.:....::||::||.|..|...:..:.|..:|.:..|..|
Human   229 ISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKC 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30178	NP_726395.1	LIM	6..61	CDD:295319	13/56 (23%)
		LIM	65..116	CDD:259829	16/50 (32%)
		LIM	124..171	CDD:295319	13/50 (26%)
FHL5	NP_001164278.1	LIM	<5..34	CDD:351770
		LIM1_FHL	37..95	CDD:188729
		LIM2_FHL5	102..155	CDD:188812	12/52 (23%)
		LIM3_FHL	163..214	CDD:188732	16/50 (32%)
		LIM4_FHL	222..277	CDD:188733	15/55 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	129	1.000	Inparanoid score	I4662
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	5	4.920