DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG30178 and PDLIM7

DIOPT Version :9

Sequence 1:NP_726395.1 Gene:CG30178 / 246501 FlyBaseID:FBgn0050178 Length:187 Species:Drosophila melanogaster
Sequence 2:NP_005442.2 Gene:PDLIM7 / 9260 HGNCID:22958 Length:457 Species:Homo sapiens


Alignment Length:169 Identity:51/169 - (30%)
Similarity:88/169 - (52%) Gaps:2/169 - (1%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 ICCRCNEKIWPRAVCSLGKTYHPHHFTCKECGLVVDPKLFFAVDDDVVCSECYLDKHAARCSACR 69
            :|.:|::.|..|.:.:||..|||..|.|.:||.|::...||.....:.|..||..::|..|:.|:
Human   281 VCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCK 345

  Fly    70 TPILERGVAAAERKWHEKCFRCVSCSKSLVSASFFEVNGYLFCKAHFRELFSSRCAGCEKPIDR- 133
            ..|....:.|.:..||..||.|.:|...:.:.:|:...|..:|:..:.::|.::|.||:..||. 
Human   346 KKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCHGCDFKIDAG 410

  Fly   134 -RAVVALSTKWHAKCFKCHHCRKRISAREFWIENGQPIC 171
             |.:.||...||..||.|..|:..:..:.|:.:..:|:|
Human   411 DRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLC 449

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG30178NP_726395.1 LIM 6..61 CDD:295319 19/54 (35%)
LIM 65..116 CDD:259829 13/50 (26%)
LIM 124..171 CDD:295319 16/48 (33%)
PDLIM7NP_005442.2 PDZ_signaling 5..79 CDD:238492
Atrophin-1 <81..254 CDD:331285
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 82..142
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 176..226
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 239..258
LIM1_Enigma 282..333 CDD:188836 17/50 (34%)
LIM2_Enigma 341..392 CDD:188840 13/50 (26%)
LIM3_Enigma 400..454 CDD:188842 17/50 (34%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1703
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000055
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X39
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.810

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