DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30178 and Tgfb1i1

DIOPT Version :9

Sequence 1:	NP_726395.1	Gene:	CG30178 / 246501	FlyBaseID:	FBgn0050178	Length:	187	Species:	Drosophila melanogaster
Sequence 2:	XP_006230411.1	Gene:	Tgfb1i1 / 84574	RGDID:	620173	Length:	473	Species:	Rattus norvegicus

Alignment Length:	167	Identity:	61/167 - (36%)
Similarity:	84/167 - (50%)	Gaps:	0/167 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 ICCRCNEKIWPRAVCSLGKTYHPHHFTCKECGLVVDPKLFFAVDDDVVCSECYLDKHAARCSACR 69
            :|..||:.|..:.|.:||:.:||.||.|:.|...:....||..|....|.|||.::.:.||..|.
  Rat   239 LCGSCNKPIAGQVVTALGRAWHPEHFLCRGCSTTLGGSSFFEKDGAPFCPECYFERFSPRCGFCN 303

  Fly    70 TPILERGVAAAERKWHEKCFRCVSCSKSLVSASFFEVNGYLFCKAHFRELFSSRCAGCEKPIDRR 134
            .||..:.|.|....||.:.|.||||.:......|.|..|..:|:..|.:||:.||.||:.||...
  Rat   304 QPIRHKMVTALGTHWHPEHFCCVSCGEPFGEEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDN 368

  Fly   135 AVVALSTKWHAKCFKCHHCRKRISAREFWIENGQPIC 171
            .:.|||..||..||.|..|....|...|:...|:|:|
  Rat   369 YISALSALWHPDCFVCRECLAPFSGGSFFEHEGRPLC 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30178	NP_726395.1	LIM	6..61	CDD:295319	20/54 (37%)
		LIM	65..116	CDD:259829	17/50 (34%)
		LIM	124..171	CDD:295319	18/46 (39%)
Tgfb1i1	XP_006230411.1	Paxillin	<69..>118	CDD:281527
		LIM1_Paxillin_like	240..292	CDD:259830	19/51 (37%)
		LIM2_Paxillin_like	299..350	CDD:188723	17/50 (34%)
		LIM3_Paxillin	358..410	CDD:188793	19/48 (40%)
		LIM4_Leupaxin	417..468	CDD:188796
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343617
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1703
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593918at2759
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.750