DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30178 and ARHGAP28

DIOPT Version :9

Sequence 1:	NP_726395.1	Gene:	CG30178 / 246501	FlyBaseID:	FBgn0050178	Length:	187	Species:	Drosophila melanogaster
Sequence 2:	NP_001353159.1	Gene:	ARHGAP28 / 79822	HGNCID:	25509	Length:	729	Species:	Homo sapiens

Alignment Length:	87	Identity:	21/87 - (24%)
Similarity:	30/87 - (34%)	Gaps:	27/87 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 KLFFAVDDDVVCSECYLDKHAARCSACRTPI------LERGVAAAERKWHEKCFRCVSCSKSLVS 100
            |.|..|::..:.||...     |.|.|...:      |:....|.:.||.:.|.|
Human   404 KFFEKVEESGLESEGIF-----RLSGCTAKVKQYREELDAKFNADKFKWDKMCHR---------- 453

  Fly   101 ASFFEVNGYLFCKAHFRELFSS 122
                  ...:..||.||||.:|
Human   454 ------EAAVMLKAFFRELPTS 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30178	NP_726395.1	LIM	6..61	CDD:295319	5/18 (28%)
		LIM	65..116	CDD:259829	10/56 (18%)
		LIM	124..171	CDD:295319
ARHGAP28	NP_001353159.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	20..42
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	55..105
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	176..236
		RhoGAP_ARHGAP18	377..588	CDD:239856	21/87 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	612..631
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1093
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.030