DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30178 and fhl3b

DIOPT Version :9

Sequence 1:	NP_726395.1	Gene:	CG30178 / 246501	FlyBaseID:	FBgn0050178	Length:	187	Species:	Drosophila melanogaster
Sequence 2:	NP_001093448.1	Gene:	fhl3b / 555053	ZFINID:	ZDB-GENE-030131-8356	Length:	290	Species:	Danio rerio

Alignment Length:	194	Identity:	55/194 - (28%)
Similarity:	79/194 - (40%)	Gaps:	22/194 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ASIC--CRCNEKIWPRAVCSLGKT--------------YHPHHFTCKECGLVVDPKLFFAVDDDV 51
            |.:|  |.|||.......|  |||              :|...|.|..|...:..:.|....|:.
Zfish    86 ALVCNNCYCNEFSSNCVAC--GKTVMPGSKRLEYEDCVWHEECFVCCGCEQPIGAQSFIPDKDEY 148

  Fly    52 VCSECYLDKHAARCSACRTPILERGVAAAERKWHEKCFRCVSCSKSLVSASFFEVNGYLFCKAHF 116
            .|..||..:.|.||:.|:..:::.||...:..||::||.|..|...|....|.......:|...|
Zfish   149 YCVPCYEGRFAPRCAHCKQTLVQGGVTYRDEPWHKECFLCTGCKVQLAGQPFTTQGEDPYCVKCF 213

  Fly   117 RELFSSRCAGCEKPI----DRRAVVALSTKWHAKCFKCHHCRKRISAREFWIENGQPICAACQT 176
            ..|::.:||.|||||    :.:.|.....:||..||||..|...:....|:......:|..|.|
Zfish   214 SNLYAQKCAACEKPITGFGEGKYVSFEERQWHKPCFKCSVCSLSLVGAGFFPHGSMILCKGCNT 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30178	NP_726395.1	LIM	6..61	CDD:295319	18/70 (26%)
		LIM	65..116	CDD:259829	13/50 (26%)
		LIM	124..171	CDD:295319	16/50 (32%)
fhl3b	NP_001093448.1	LIM	<5..33	CDD:295319
		LIM1_FHL3	36..94	CDD:188807	3/7 (43%)
		LIM2_FHL3	98..155	CDD:188811	12/58 (21%)
		LIM3_FHL	162..213	CDD:188732	13/50 (26%)
		LIM4_FHL3	221..276	CDD:188818	17/54 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	54	1.000	Domainoid score	I11189
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	133	1.000	Inparanoid score	I4575
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.960