DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30178 and pdlim5

DIOPT Version :9

Sequence 1:	NP_726395.1	Gene:	CG30178 / 246501	FlyBaseID:	FBgn0050178	Length:	187	Species:	Drosophila melanogaster
Sequence 2:	XP_012817118.2	Gene:	pdlim5 / 548530	XenbaseID:	XB-GENE-854114	Length:	884	Species:	Xenopus tropicalis

Alignment Length:	169	Identity:	51/169 - (30%)
Similarity:	82/169 - (48%)	Gaps:	2/169 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 ICCRCNEKIWPRAVCSLGKTYHPHHFTCKECGLVVDPKLFFAVDDDVVCSECYLDKHAARCSACR 69
            :|..||:.|....:.:|||::||..|.|..|...:....|......:.|..||....|..|:.|:
Frog   707 MCAICNKVIRGPFLLALGKSWHPEEFNCAHCKSSMAEMGFVEEKGGLYCEICYEKLFAPECARCQ 771

  Fly    70 TPILERGVAAAERKWHEKCFRCVSCSKSLVSASFFEVNGYLFCKAHFRELFSSRCAGCEKPIDR- 133
            ..||...:.|.::.||..||.||:|...:.::.|...:|..:|:..:..||.:.|.|||.||:.
Frog   772 RKILGEVINALKQTWHVSCFVCVACQTPIRNSVFHLEDGEPYCETDYYSLFGTICHGCEFPIEAG 836

  Fly   134 -RAVVALSTKWHAKCFKCHHCRKRISAREFWIENGQPIC 171
             |.:.||...||..||.|..|.:.:..:.|:.:..:.:|
Frog   837 DRFLEALGHTWHNTCFVCTICCENLEGQTFFSKKDKLLC 875

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30178	NP_726395.1	LIM	6..61	CDD:295319	16/54 (30%)
		LIM	65..116	CDD:259829	15/50 (30%)
		LIM	124..171	CDD:295319	16/48 (33%)
pdlim5	XP_012817118.2	PDZ	10..83	CDD:214570
		PRK14951	<80..216	CDD:237865
		DUF4749	212..320	CDD:406377
		LIM1_ENH	708..759	CDD:188837	14/50 (28%)
		LIM2_Enigma_like	767..818	CDD:188748	15/50 (30%)
		LIM3_ENH	826..880	CDD:188843	17/50 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910