DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30178 and fhl3

DIOPT Version :9

Sequence 1:	NP_726395.1	Gene:	CG30178 / 246501	FlyBaseID:	FBgn0050178	Length:	187	Species:	Drosophila melanogaster
Sequence 2:	NP_001008165.1	Gene:	fhl3 / 493527	XenbaseID:	XB-GENE-947662	Length:	279	Species:	Xenopus tropicalis

Alignment Length:	180	Identity:	53/180 - (29%)
Similarity:	81/180 - (45%)	Gaps:	6/180 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ASICCRCNEKIWP--RAVCSLGKTYHPHHFTCKECGLVVDPKLFFAVDDDVVCSECYLDKHAARC 65
            :|.|..|.:.:.|  |.:...|:|:|.|.|.|..|...:..:.|...:.:..|..||..|.|.||
Frog    98 SSKCISCEKTVMPGSRKLEYNGQTWHEHCFICNSCQQPIGSRSFIPENQNHYCIPCYESKLAPRC 162

  Fly    66 SACRTPILERGVAAAERKWHEKCFRCVSCSKSLVSASFFEVNGYLFCKAHFRELFSSRCAGCEKP 130
            :.|:..:.:.||...:..||::||.|..|...|....|...:...:|...|..|::.:||||.||
Frog   163 THCKKSLTKGGVTYRDEPWHKECFVCTGCKTQLAGQQFTSQDEKPYCIKCFGNLYAKKCAGCTKP 227

  Fly   131 I----DRRAVVALSTKWHAKCFKCHHCRKRISAREFWIENGQPICAACQT 176
            |    ..:.|......||..||.|..|...:..:.|..:|...:|.||.:
Frog   228 ITGFGGAKYVSFEERHWHHSCFNCSRCSTSLVGKGFIPDNEDILCRACNS 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30178	NP_726395.1	LIM	6..61	CDD:295319	15/56 (27%)
		LIM	65..116	CDD:259829	13/50 (26%)
		LIM	124..171	CDD:295319	16/50 (32%)
fhl3	NP_001008165.1	LIM	<5..33	CDD:351770
		LIM1_FHL3	36..94	CDD:188807
		LIM2_FHL3	98..155	CDD:188811	15/56 (27%)
		LIM3_FHL	162..213	CDD:188732	13/50 (26%)
		LIM4_FHL3	221..276	CDD:188818	18/54 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	126	1.000	Inparanoid score	I4543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.960