DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30178 and fhl5

DIOPT Version :9

Sequence 1:	NP_726395.1	Gene:	CG30178 / 246501	FlyBaseID:	FBgn0050178	Length:	187	Species:	Drosophila melanogaster
Sequence 2:	NP_001004112.1	Gene:	fhl5 / 445475	ZFINID:	ZDB-GENE-040822-3	Length:	280	Species:	Danio rerio

Alignment Length:	185	Identity:	51/185 - (27%)
Similarity:	87/185 - (47%)	Gaps:	16/185 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CCRCNEKIWPRA--VCSL------------GKTYHPHHFTCKECGLVVDPKLFFAVDDDVVCSEC 56
            |.:|.|.::...  ||||            .:.:|.:.|.|.:|...:..|.|.|.|:.::|:||
Zfish    29 CTKCYENLFANCCEVCSLPIGCNCKDLSYKDRHWHENCFKCAKCSRSLVDKPFAAKDELMLCTEC 93

  Fly    57 YLDKHAARCSACRTPIL--ERGVAAAERKWHEKCFRCVSCSKSLVSASFFEVNGYLFCKAHFREL 119
            |..:::::||.|:..::  .|.:......|||.||.|..|.:.:.:.||...:...||...|.:.
Zfish    94 YSHEYSSKCSTCKKTVMPGSRKMEYKGNSWHETCFLCQRCQQPIGTKSFIPKDNNYFCVPCFEKQ 158

  Fly   120 FSSRCAGCEKPIDRRAVVALSTKWHAKCFKCHHCRKRISAREFWIENGQPICAAC 174
            |:.:|..|:|.|....|......||.:||.|..|:::::.:.|......|.|..|
Zfish   159 FAYQCCACKKAITTGGVTYHDKPWHRECFTCIGCKRQLAGQRFTSRENYPYCLDC 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30178	NP_726395.1	LIM	6..61	CDD:295319	19/68 (28%)
		LIM	65..116	CDD:259829	15/52 (29%)
		LIM	124..171	CDD:295319	13/46 (28%)
fhl5	NP_001004112.1	LIM	<6..34	CDD:295319	2/4 (50%)
		LIM1_FHL	37..95	CDD:188729	15/57 (26%)
		LIM	102..158	CDD:295319	16/55 (29%)
		LIM3_FHL	163..214	CDD:188732	15/51 (29%)
		LIM4_FHL	222..277	CDD:188733
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	54	1.000	Domainoid score	I11189
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	133	1.000	Inparanoid score	I4575
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	5.050