DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30178 and fhl1a

DIOPT Version :9

Sequence 1:	NP_726395.1	Gene:	CG30178 / 246501	FlyBaseID:	FBgn0050178	Length:	187	Species:	Drosophila melanogaster
Sequence 2:	NP_001007288.1	Gene:	fhl1a / 399646	ZFINID:	ZDB-GENE-040206-1	Length:	297	Species:	Danio rerio

Alignment Length:	177	Identity:	55/177 - (31%)
Similarity:	81/177 - (45%)	Gaps:	9/177 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CCRCNEKIWP--RAVCSLGKTYHPHHFTCKECGLVVDPKLFFAVDDDVVCSECYLDKHAARCSAC 68
            |..|.:.|.|  :.|....|.:|...|||.||...:..:.|....||:.|:.|:..|.|..|..|
Zfish   118 CQGCYKVITPGCKNVEYKHKVWHEECFTCFECKQPIRTQSFLTKGDDMYCTPCHEKKFAKHCVRC 182

  Fly    69 RTPILERGVAAAERKWHEKCFRCVSCSKSLVSASFFEVNGYLFCKAHFRELFSSRCAGCEKPID- 132
            :..|...|:...::.||.:||.|.:|.|.|..|.|.......:|...::...:.:|:||:.||.
Zfish   183 KEAITSGGLTYQDQPWHSECFVCHTCKKPLAGARFTAHEDQFYCVDCYKSDVAKKCSGCQNPITG 247

  Fly   133 ---RRAVVALSTK-WHAKCFKCHHCRKRISAREFWIENGQPI-CAAC 174
               ...||....| ||..||.|..|...::.:.|.| ||:.| |:.|
Zfish   248 FGRGTNVVNYEDKSWHEYCFNCKKCSLSMAHKRFVI-NGEDIYCSDC 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30178	NP_726395.1	LIM	6..61	CDD:295319	17/56 (30%)
		LIM	65..116	CDD:259829	15/50 (30%)
		LIM	124..171	CDD:295319	19/52 (37%)
fhl1a	NP_001007288.1	LIM	<21..49	CDD:295319
		LIM1_FHL1	56..110	CDD:188730
		LIM2_FHL1	118..175	CDD:188808	17/56 (30%)
		LIM3_FHL1	179..231	CDD:188813	15/51 (29%)
		LIM4_FHL1	234..297	CDD:188734	21/61 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	54	1.000	Domainoid score	I11189
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	133	1.000	Inparanoid score	I4575
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.960