DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30178 and Zasp52

DIOPT Version :9

Sequence 1:	NP_726395.1	Gene:	CG30178 / 246501	FlyBaseID:	FBgn0050178	Length:	187	Species:	Drosophila melanogaster
Sequence 2:	NP_001027420.2	Gene:	Zasp52 / 36740	FlyBaseID:	FBgn0265991	Length:	2194	Species:	Drosophila melanogaster

Alignment Length:	171	Identity:	51/171 - (29%)
Similarity:	85/171 - (49%)	Gaps:	4/171 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 ICCRCNEKIWPRAVCSLGKTYHPHHFTC--KECGLVVDPKLFFAVDDDVVCSECYLDKHAARCSA 67
            :|..||.:|....:.:||:.:.|.||.|  ..|...:....|.....|:.|..|:....|..||.
  Fly  2019 LCNSCNVQIRGPFITALGRIWCPDHFICVNGNCRRPLQDIGFVEEKGDLYCEYCFEKYLAPTCSK 2083

  Fly    68 CRTPILERGVAAAERKWHEKCFRCVSCSKSLVSASFFEVNGYLFCKAHFRELFSSRCAGCEKPID 132
            |...|....:.|..:.:|.:||.|..|.|...:..||..:|..:|:|.:.|||:::|..|..|::
  Fly  2084 CAGKIKGDCLNAIGKHFHPECFTCGQCGKIFGNRPFFLEDGNAYCEADWNELFTTKCFACGFPVE 2148

  Fly   133 R--RAVVALSTKWHAKCFKCHHCRKRISAREFWIENGQPIC 171
            .  |.|.||:..:|::||.|..|::.:..:.|:.:.|:|.|
  Fly  2149 AGDRWVEALNHNYHSQCFNCTFCKQNLEGQSFYNKGGRPFC 2189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30178	NP_726395.1	LIM	6..61	CDD:295319	15/56 (27%)
		LIM	65..116	CDD:259829	16/50 (32%)
		LIM	124..171	CDD:295319	15/48 (31%)
Zasp52	NP_001027420.2	PDZ_signaling	6..87	CDD:238492
		DUF4749	150..>217	CDD:292558
		LIM_ALP_like	282..333	CDD:188746
		LIM1_Enigma_like_1	2020..2073	CDD:188839	14/52 (27%)
		LIM	2081..2132	CDD:259829	16/50 (32%)
		LIM3_Enigma_like_1	2140..2193	CDD:188845	16/50 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1703
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	1	1.000	-	-		otm47179
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.810