DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30178 and Fhl3

DIOPT Version :9

Sequence 1:	NP_726395.1	Gene:	CG30178 / 246501	FlyBaseID:	FBgn0050178	Length:	187	Species:	Drosophila melanogaster
Sequence 2:	NP_001101449.1	Gene:	Fhl3 / 313582	RGDID:	1307180	Length:	288	Species:	Rattus norvegicus

Alignment Length:	206	Identity:	53/206 - (25%)
Similarity:	85/206 - (41%)	Gaps:	37/206 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CCRCNEKIWPR-----------------------AVCS--LG----------KTYHPHHFTCKEC 35
            |.:|||.::.|                       |.|.  :|          :.:|...|.|..|
  Rat     7 CAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFHEGCFRCCRC 71

  Fly    36 GLVVDPKLFFAVDDDVVCSECYLDKHAARCSACRTPIL--ERGVAAAERKWHEKCFRCVSCSKSL 98
            ...:..:.|...|.:::|:|||....:::||||...::  .|.:....:.|||.||.|..|.:.|
  Rat    72 QRSLADEPFTCQDSELLCNECYCTAFSSQCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPL 136

  Fly    99 VSASFFEVNGYLFCKAHFRELFSSRCAGCEKPIDRRAVVALSTKWHAKCFKCHHCRKRISAREFW 163
            .|.||....|..:|...:...|:.|||.|.|.:.:..|......||.:|..|..|:..::.::|.
  Rat   137 GSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFT 201

  Fly   164 IENGQPICAAC 174
            ..:..|.|.||
  Rat   202 SRDDDPYCVAC 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30178	NP_726395.1	LIM	6..61	CDD:295319	18/89 (20%)
		LIM	65..116	CDD:259829	18/52 (35%)
		LIM	124..171	CDD:295319	12/46 (26%)
Fhl3	NP_001101449.1	LIM	<5..33	CDD:413332	5/25 (20%)
		LIM1_FHL3	36..94	CDD:188807	12/57 (21%)
		LIM2_FHL3	98..155	CDD:188811	18/56 (32%)
		LIM3_FHL	162..213	CDD:188732	15/51 (29%)
		LIM	221..284	CDD:413332
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	56	1.000	Domainoid score	I10711
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	131	1.000	Inparanoid score	I4531
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.920