DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30178 and Fhl1

DIOPT Version :9

Sequence 1:	NP_726395.1	Gene:	CG30178 / 246501	FlyBaseID:	FBgn0050178	Length:	187	Species:	Drosophila melanogaster
Sequence 2:	XP_006257733.1	Gene:	Fhl1 / 25177	RGDID:	2615	Length:	339	Species:	Rattus norvegicus

Alignment Length:	199	Identity:	49/199 - (24%)
Similarity:	82/199 - (41%)	Gaps:	16/199 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ASICCRCNEKIWPRA--VCSLGKTYHPHHFTCKECGLVVDPKLFFAVDDDVVCSECYLDKHAARC 65
            |:.|..|.:.|...|  |....:.:|...|.|.:|...:..:.|.:.|..::|::|...:.:.||
  Rat    53 ANTCVECRKPISADAKEVHYKNRYWHDTCFRCAKCLHPLASETFVSKDGKILCNKCATREDSPRC 117

  Fly    66 SACRTPIL--ERGVAAAERKWHEKCFRCVSCSKSLVSASFFEVNGYLFCKAHFRELFSSRCAGCE 128
            ..|...|:  ::.|......||:.||.|.:|.:.:.:.|||......:|.......|:..|..|.
  Rat   118 KGCFKAIVAGDQNVEYKGTIWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCN 182

  Fly   129 KPIDRRAVVALSTKWHAKCFKCHHCRKRISAREFWIENGQ------------PICAACQTVVPSP 181
            |.|....:......|||:||.|..|.|:::.:.|.....|            ..||.|:..:...
  Rat   183 KAITSGGITYQDQPWHAECFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGK 247

  Fly   182 RNLS 185
            |.:|
  Rat   248 RTVS 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30178	NP_726395.1	LIM	6..61	CDD:295319	13/56 (23%)
		LIM	65..116	CDD:259829	14/52 (27%)
		LIM	124..171	CDD:295319	14/58 (24%)
Fhl1	XP_006257733.1	LIM	<21..49	CDD:351770
		LIM1_FHL1	56..109	CDD:188730	12/52 (23%)
		LIM2_FHL1	117..174	CDD:188808	14/56 (25%)
		LIM3_FHL1	178..230	CDD:188813	14/51 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	56	1.000	Domainoid score	I10711
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	131	1.000	Inparanoid score	I4531
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.960