DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30178 and Ldb3

DIOPT Version :9

Sequence 1:	NP_726395.1	Gene:	CG30178 / 246501	FlyBaseID:	FBgn0050178	Length:	187	Species:	Drosophila melanogaster
Sequence 2:	NP_036048.3	Gene:	Ldb3 / 24131	MGIID:	1344412	Length:	723	Species:	Mus musculus

Alignment Length:	169	Identity:	49/169 - (28%)
Similarity:	83/169 - (49%)	Gaps:	2/169 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 ICCRCNEKIWPRAVCSLGKTYHPHHFTCKECGLVVDPKLFFAVDDDVVCSECYLDKHAARCSACR 69
            :|..||..|....:.::|:::||..|.|..|...:....|....::|.|..||....|..|:.|.
Mouse   546 LCGHCNNVIRGPFLVAMGRSWHPEEFNCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPICAKCN 610

  Fly    70 TPILERGVAAAERKWHEKCFRCVSCSKSLVSASFFEVNGYLFCKAHFRELFSSRCAGCEKPIDR- 133
            |.|:...:.|..:.||..||.|.:|.|...::.|...:|..:|:..:..|||::|.||:.|::.
Mouse   611 TKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAG 675

  Fly   134 -RAVVALSTKWHAKCFKCHHCRKRISAREFWIENGQPIC 171
             :.:.||...||..||.|..|...:..:.|:.:..:|:|
Mouse   676 DKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDKPLC 714

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30178	NP_726395.1	LIM	6..61	CDD:295319	15/54 (28%)
		LIM	65..116	CDD:259829	15/50 (30%)
		LIM	124..171	CDD:295319	14/48 (29%)
Ldb3	NP_036048.3	PDZ_signaling	5..81	CDD:238492
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	89..134
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	164..193
		DUF4749	191..293	CDD:374237
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	280..423
		PHA03247	<378..528	CDD:223021
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	436..525
		LIM1_ZASP_Cypher	547..598	CDD:188838	13/50 (26%)
		LIM2_Enigma_like	606..657	CDD:188748	15/50 (30%)
		LIM3_ZASP_Cypher	665..719	CDD:188844	15/50 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1703
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810