DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30178 and FHL3

DIOPT Version :9

Sequence 1:	NP_726395.1	Gene:	CG30178 / 246501	FlyBaseID:	FBgn0050178	Length:	187	Species:	Drosophila melanogaster
Sequence 2:	NP_004459.2	Gene:	FHL3 / 2275	HGNCID:	3704	Length:	280	Species:	Homo sapiens

Alignment Length:	191	Identity:	54/191 - (28%)
Similarity:	79/191 - (41%)	Gaps:	22/191 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ASICCRCNEKIWP--RAVCSLGKTYHPHHFTCKECGLVVDPKLFFAVDDDVVCSECYLDKHAARC 65
            :|.|..|.|.:.|  |.:...|:|:|.|.|.|..|...:..:.|........|..||.:|.|.||
Human    98 SSQCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRC 162

  Fly    66 SACRTPILERGVAAAERKWHEKCFRCVSCSKSLVSASFFEVNGYLFCKAHFRELFSSRCAGCEKP 130
            :.|...:.:.||...::.||.:|..|..|...|....|...:...:|.|.|.|||:.:|:.|::|
Human   163 ARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRP 227

  Fly   131 I------------DRRAVVALSTKWHAKCFKCHHCRKRISAREFWIENGQPICAACQTVVP 179
            |            ||.        ||..||.|..|...:..:.|..:..|.:|..|....|
Human   228 IVGLGGGKYVSFEDRH--------WHHNCFSCARCSTSLVGQGFVPDGDQVLCQGCSQAGP 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30178	NP_726395.1	LIM	6..61	CDD:295319	16/56 (29%)
		LIM	65..116	CDD:259829	13/50 (26%)
		LIM	124..171	CDD:295319	14/58 (24%)
FHL3	NP_004459.2	LIM	<5..33	CDD:295319
		LIM1_FHL3	36..94	CDD:188807
		LIM2_FHL3	98..155	CDD:188811	16/56 (29%)
		LIM3_FHL	162..213	CDD:188732	13/50 (26%)
		LIM4_FHL3	221..276	CDD:188818	15/62 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	129	1.000	Inparanoid score	I4662
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	5	4.920