DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30178 and pxl-1

DIOPT Version :9

Sequence 1:	NP_726395.1	Gene:	CG30178 / 246501	FlyBaseID:	FBgn0050178	Length:	187	Species:	Drosophila melanogaster
Sequence 2:	NP_001021185.2	Gene:	pxl-1 / 175831	WormBaseID:	WBGene00016197	Length:	413	Species:	Caenorhabditis elegans

Alignment Length:	166	Identity:	59/166 - (35%)
Similarity:	86/166 - (51%)	Gaps:	0/166 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CCRCNEKIWPRAVCSLGKTYHPHHFTCKECGLVVDPKLFFAVDDDVVCSECYLDKHAARCSACRT 70
            |..|.:.|..:.|.:|||.:||.|:||.|||..:..:.||..:....|.|.|.::.:.:|..|..
Worm   176 CAACGKPIIGQVVIALGKMWHPEHYTCCECGAELGQRPFFERNGRAFCEEDYHNQFSPKCQGCHR 240

  Fly    71 PILERGVAAAERKWHEKCFRCVSCSKSLVSASFFEVNGYLFCKAHFRELFSSRCAGCEKPIDRRA 135
            .|.:|.|:...:.:|.:||.|..|::......|.|.||..:||..|..||:.:|.||.:||....
Worm   241 AITDRCVSVMNKNFHIECFTCAECNQPFGEDGFHEKNGQTYCKRDFFRLFAPKCNGCSQPITSNF 305

  Fly   136 VVALSTKWHAKCFKCHHCRKRISAREFWIENGQPIC 171
            :.||.|.||..||.|.||....:...|:..||.|:|
Worm   306 ITALGTHWHPDCFVCQHCGVSFNGASFFEHNGAPLC 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30178	NP_726395.1	LIM	6..61	CDD:295319	20/54 (37%)
		LIM	65..116	CDD:259829	16/50 (32%)
		LIM	124..171	CDD:295319	19/46 (41%)
pxl-1	NP_001021185.2	LIM1_Leupaxin	174..228	CDD:188790	19/51 (37%)
		LIM	235..290	CDD:278823	17/54 (31%)
		LIM3_Paxillin_like	294..346	CDD:188724	20/48 (42%)
		LIM4_Paxillin_like	353..404	CDD:188725
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593918at2759
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1093
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.950