DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30178 and tgfb1i1

DIOPT Version :9

Sequence 1:	NP_726395.1	Gene:	CG30178 / 246501	FlyBaseID:	FBgn0050178	Length:	187	Species:	Drosophila melanogaster
Sequence 2:	XP_012825390.2	Gene:	tgfb1i1 / 100038241	XenbaseID:	XB-GENE-493249	Length:	503	Species:	Xenopus tropicalis

Alignment Length:	169	Identity:	58/169 - (34%)
Similarity:	83/169 - (49%)	Gaps:	0/169 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CCRCNEKIWPRAVCSLGKTYHPHHFTCKECGLVVDPKLFFAVDDDVVCSECYLDKHAARCSACRT 70
            |..|...|....|.:||.|:||.||.||.|...:..:.|...|.:..||:.|.....|.|:.|..
Frog   329 CALCELPIVQNMVTALGCTWHPEHFCCKVCKKPIGEEGFHEKDGEQYCSDDYFRLFGAVCAGCSE 393

  Fly    71 PILERGVAAAERKWHEKCFRCVSCSKSLVSASFFEVNGYLFCKAHFRELFSSRCAGCEKPIDRRA 135
            .:.|..::|....||.:||.|..|....::.||||..|...|:.|:.....|.|||||:||..|.
Frog   394 AVKESYISALGGLWHPQCFVCHVCHTPFINGSFFEHEGLPLCETHYHSRRGSLCAGCEQPITGRC 458

  Fly   136 VVALSTKWHAKCFKCHHCRKRISAREFWIENGQPICAAC 174
            |.|:..|:|.:...|..|.::::...|...:|:|.|.||
Frog   459 VTAMGKKFHPQHLNCTFCLRQLNKGTFREHDGKPYCQAC 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30178	NP_726395.1	LIM	6..61	CDD:295319	19/54 (35%)
		LIM	65..116	CDD:259829	16/50 (32%)
		LIM	124..171	CDD:295319	17/46 (37%)
tgfb1i1	XP_012825390.2	Paxillin	<61..>117	CDD:397550
		LIM1_Paxillin_like	270..322	CDD:259830
		LIM2_Paxillin_like	329..380	CDD:188723	18/50 (36%)
		LIM3_Paxillin_like	388..440	CDD:188724	17/51 (33%)
		LIM4_Paxillin_like	447..498	CDD:188725	20/51 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593918at2759
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1093
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.040