DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG30160 and ROM1

DIOPT Version :10

Sequence 1:NP_724526.1 Gene:CG30160 / 246490 FlyBaseID:FBgn0050160 Length:222 Species:Drosophila melanogaster
Sequence 2:NP_000318.2 Gene:ROM1 / 6094 HGNCID:10254 Length:351 Species:Homo sapiens


Alignment Length:242 Identity:51/242 - (21%)
Similarity:82/242 - (33%) Gaps:92/242 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 LYLLN-LVFVAGGILLIVVGSIM--LSTMGNFTAFDGGVNTQTIPICIIVIGSVTFVVAFFGCCG 73
            |:||: |:.:|||::|:..|.::  |..:|.|.|  .......:|...:..|:|.......| .|
Human    21 LWLLSWLLALAGGVILLCSGHLLVQLRHLGTFLA--PSCQFPVLPQAALAAGAVALGTGLVG-VG 82

  Fly    74 TIRE--NACCTTIYAICM-------------LILFGLQLALSIWIFAANDKFLSSMGKAVDKAWD 123
            ..|.  ||.....:...:             |::.||.|||             ::..::|:|.:
Human    83 ASRASLNAALYPPWRGVLGPLLVAGTAGGGGLLVVGLGLAL-------------ALPGSLDEALE 134

  Fly   124 EN--NAAQGYP-------------MDALQLAFSCCGNTGYQQY---------------------- 151
            |.  .|...|.             :|.|||.:.|||..||:.:                      
Human   135 EGLVTALAHYKDTEVPGHCQAKRLVDELQLRYHCCGRHGYKDWFGVQWVSSRYLDPGDRDVADRI 199

  Fly   152 ----------ETVPSSCCGYKDRTKVCEAEIYSQRPGCRQEFVDFWA 188
                      :.||.|||           ..:|.||..:....|.:|
Human   200 QSNVEGLYLTDGVPFSCC-----------NPHSPRPCLQNRLSDSYA 235

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG30160NP_724526.1 Tetraspanin 8..216 CDD:459767 51/242 (21%)
ROM1NP_000318.2 peripherin_like_LEL 126..265 CDD:239415 24/121 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 331..351
Blue background indicates that the domain is not in the aligned region.

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