DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30160 and Cd63

DIOPT Version :9

Sequence 1:	NP_724526.1	Gene:	CG30160 / 246490	FlyBaseID:	FBgn0050160	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_001036045.1	Gene:	Cd63 / 12512	MGIID:	99529	Length:	238	Species:	Mus musculus

Alignment Length:	248	Identity:	75/248 - (30%)
Similarity:	119/248 - (47%)	Gaps:	50/248 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MNCLSAMFKYLLYLLNLVFVAGGILLIVVG---SIML-------STMGNFTAFDGGVNTQTIPIC 55
            |.|:    |:|||:|.|.|.|..:.||.:|   .::|       :|.|:.           :|:.
Mouse     7 MKCV----KFLLYVLLLAFCACAVGLIAIGVAVQVVLKQAITHETTAGSL-----------LPVV 56

  Fly    56 IIVIGSVTFVVAFFGCCGTIRENACCTTIYAICMLILFGLQLALSIWIFAANDKFLSSMGKAVDK 120
            ||.:|:..|:|||.||||..:||.|....:||.:.::..:::|::|..:...|:..|...|:..:
Mouse    57 IIAVGAFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAVAIAGYVFRDQVKSEFNKSFQQ 121

  Fly   121 AWD----ENNAAQGYPMDALQLAFSCCGNTGYQQYET--------VPSSCCGYKDRTKVC----- 168
            ...    :|..|.  .:|.||...:|||.:.|..:|.        ||.|||  .:.|..|
Mouse   122 QMQNYLKDNKTAT--ILDKLQKENNCCGASNYTDWENIPGMAKDRVPDSCC--INITVGCGNDFK 182

  Fly   169 EAEIYSQRPGCRQEFVDFWASNTDLIRWSSLIIALFE-LGIFIMSCCLASAMR 220
            |:.|::|  ||.:....:...|..|:..::|.||..| ||| |.||||..::|
Mouse   183 ESTIHTQ--GCVETIAIWLRKNILLVAAAALGIAFVEVLGI-IFSCCLVKSIR 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30160	NP_724526.1	Tetraspannin	8..219	CDD:278750	72/238 (30%)
CG30160	NP_724526.1	tetraspanin_LEL	104..191	CDD:239401	25/103 (24%)
Cd63	NP_001036045.1	Tetraspannin	10..227	CDD:395265	70/238 (29%)
		CD63_LEL	105..203	CDD:239419	25/103 (24%)
		Lysosomal targeting motif. /evidence=ECO:0000269\|PubMed:21041449	234..238
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810