DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30156 and DNAJC3

DIOPT Version :9

Sequence 1:	NP_001260752.1	Gene:	CG30156 / 246488	FlyBaseID:	FBgn0050156	Length:	358	Species:	Drosophila melanogaster
Sequence 2:	XP_011519406.1	Gene:	DNAJC3 / 5611	HGNCID:	9439	Length:	533	Species:	Homo sapiens

Alignment Length:	163	Identity:	39/163 - (23%)
Similarity:	69/163 - (42%)	Gaps:	54/163 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 YEHALRQINEDLEGLQNHDE----IMALLELKNIILRLRLKGEAQRTIGPTRKSDALPHKFTLEM 84
            |:.|:    :|.|..|.|:|    |...||            :|||.:..::|
Human   385 YDEAI----QDYETAQEHNENDQQIREGLE------------KAQRLLKQSQK------------ 421

  Fly    85 LDVVQKVLRCRNHYEVLRISHHATYSEVKRAYHKLALRLHPD----KNKSPGAEQAFRRISEAAD 145
                      |::|::|.:..:|...|:.:||.||||:.|||    :.:...||:.|..|:.|.:
Human   422 ----------RDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQNEEEKKKAEKKFIDIAAAKE 476

  Fly   146 CLTDCQKRIEYNIATAVGDCHDQDPSQYKDYRG 178
            .|:|.:.|.:::        ..:||...:..:|
Human   477 VLSDPEMRKKFD--------DGEDPLDAESQQG 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30156	NP_001260752.1	DnaJ	96..157	CDD:278647	21/64 (33%)
CG30156	NP_001260752.1	DUF1977	237..334	CDD:286411
DNAJC3	XP_011519406.1	TPR_11	36..100	CDD:290150
		TPR repeat	37..65	CDD:276809
		TPR repeat	70..100	CDD:276809
		TPR_11	73..132	CDD:290150
		TPR repeat	105..132	CDD:276809
		TPR_11	182..246	CDD:290150
		TPR repeat	186..211	CDD:276809
		TPR_11	216..281	CDD:290150
		TPR repeat	216..246	CDD:276809
		TPR repeat	251..279	CDD:276809
		TPR repeat	285..309	CDD:276809
		TPR repeat	330..364	CDD:276809
		TPR_19	347..411	CDD:291240	10/41 (24%)
		TPR_1	369..402	CDD:278916	7/20 (35%)
		TPR repeat	369..397	CDD:276809	4/15 (27%)
		TPR repeat	403..426	CDD:276809	8/56 (14%)
		DnaJ	421..>527	CDD:223560	26/111 (23%)
		DnaJ	423..488	CDD:278647	21/64 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910