DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30156 and DNAJB9

DIOPT Version :9

Sequence 1:	NP_001260752.1	Gene:	CG30156 / 246488	FlyBaseID:	FBgn0050156	Length:	358	Species:	Drosophila melanogaster
Sequence 2:	NP_036460.1	Gene:	DNAJB9 / 4189	HGNCID:	6968	Length:	223	Species:	Homo sapiens

Alignment Length:	154	Identity:	45/154 - (29%)
Similarity:	76/154 - (49%)	Gaps:	35/154 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 FTLEMLDVVQKVLRCRNHYEVLRISHHATYSEVKRAYHKLALRLHPDKNKSPGAEQAFRRISEAA 144
            |.:.:|.:.:.:|..:::|::|.:...|:..::|:|:||||::.||||||||.||..||.|:||.
Human    10 FAICILMITELILASKSYYDILGVPKSASERQIKKAFHKLAMKYHPDKNKSPDAEAKFREIAEAY 74

  Fly   145 DCLTDCQKRIEYNIATAVGDCHDQDPSQYKDYRGESEFNEANG-NDLGAAFRRPYR--------- 199
            :.|:|..:|.||                  |..|.|.|....| ...|::|.:.:.
Human    75 ETLSDANRRKEY------------------DTLGHSAFTSGKGQRGSGSSFEQSFNFNFDDLFKD 121

  Fly   200 ----GANQRMPQR---QSLYQTQQ 216
                |.||....:   ::.:||:|
Human   122 FGFFGQNQNTGSKKRFENHFQTRQ 145

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30156	NP_001260752.1	DnaJ	96..157	CDD:278647	28/60 (47%)
CG30156	NP_001260752.1	DUF1977	237..334	CDD:286411
DNAJB9	NP_036460.1	type 2 signal-anchor for ER localization	7..23		2/12 (17%)
		DnaJ	26..>136	CDD:333066	39/127 (31%)
		Divergent targeting domain. /evidence=ECO:0000250\|UniProtKB:Q9QYI6	91..223		11/55 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1173544at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820