DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30156 and DNAJB2

DIOPT Version :9

Sequence 1:	NP_001260752.1	Gene:	CG30156 / 246488	FlyBaseID:	FBgn0050156	Length:	358	Species:	Drosophila melanogaster
Sequence 2:	NP_006727.2	Gene:	DNAJB2 / 3300	HGNCID:	5228	Length:	324	Species:	Homo sapiens

Alignment Length:	140	Identity:	39/140 - (27%)
Similarity:	60/140 - (42%)	Gaps:	35/140 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 NHYEVLRISHHATYSEVKRAYHKLALRLHPDKN--KSPGAEQAFRRISEAADCLTDCQKRIEYN- 157
            ::||:|.:...|:..::|:||.:.||:.|||||  ....||:.|:.::||.:.|:|..||..|:
Human     3 SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDR 67

  Fly   158 ------IATAVGDCHDQDPSQYKDYRG-----------ESEFNEANG---------NDLGAAFRR 196
                  ..|..|      ||:.:...|           |..|.|..|         :|||.....
Human    68 YGREGLTGTGTG------PSRAEAGSGGPGFTFTFRSPEEVFREFFGSGDPFAELFDDLGPFSEL 126

  Fly   197 PYRGANQRMP 206
            ..||:....|
Human   127 QNRGSRHSGP 136

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30156	NP_001260752.1	DnaJ	96..157	CDD:278647	23/62 (37%)
CG30156	NP_001260752.1	DUF1977	237..334	CDD:286411
DNAJB2	NP_006727.2	DnaJ	3..>110	CDD:223560	33/112 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	70..90		5/25 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	218..324
		CAAX motif. /evidence=ECO:0000269\|PubMed:12754272	321..324
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154073
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740