DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30156 and dnj-27

DIOPT Version :9

Sequence 1:	NP_001260752.1	Gene:	CG30156 / 246488	FlyBaseID:	FBgn0050156	Length:	358	Species:	Drosophila melanogaster
Sequence 2:	NP_001040704.1	Gene:	dnj-27 / 173065	WormBaseID:	WBGene00001045	Length:	788	Species:	Caenorhabditis elegans

Alignment Length:	284	Identity:	60/284 - (21%)
Similarity:	107/284 - (37%)	Gaps:	91/284 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 NHYEVLRISHHATYSEVKRAYHKLALRLHPDKN-KSPGAEQAFRRISEAADCLTDCQKRIEYNIA 159
            ::||:|.:...|....:::|:.|||::.|||:| ..|.|...|.:|::|.:.|.|...|.:|:
Worm    20 DYYELLGVERDADDRTIRKAFKKLAIKKHPDRNTDDPNAHDEFVKINKAYEVLKDENLRKKYD-- 82

  Fly   160 TAVGDCHDQDPSQYKDYRGESEFNEANGNDLGAAFRRPYRGAN-----QRMPQRQSLYQTQQLVI 219
                                 :|.|....|       .::|.|     |.......:|...|.::
Worm    83 ---------------------QFGEKGLED-------GFQGGNNYQSWQFYNDNFGIYDDDQEIV 119

  Fly   220 GVVAALVFLFVTMHFIAGAPAYSFTLTRTHSARRLSRTNHIAYYMNPTTLSKYTE--QQLA---- 278
                                    ||.|....|.:|.:|.| :::|  ..|.|..  .|||
Worm   120 ------------------------TLNRADFQRMVSDSNEI-WFIN--FYSTYCSHCHQLAPTWR 157

  Fly   279 ----ELE--VEIEEVYISDLKHKCRQER--SWRDNLFL---RARQGNNDQKLLQHVSQMSTPACQ 332
                |:|  :.:..|..::....|:.:|  ::...:|.   ...||:.|.:|:...:
Worm   158 KFAREIEGTIRVGAVNCAEDPQLCQSQRVNAYPSLVFYPTGEFYQGHRDVELMVDFA-------- 214

  Fly   333 ALLQLGKSGHSRLLLEN-ESLNQD 355
              :|..||....|..|| ::|::|
Worm   215 --IQRLKSEVLHLNSENWKALSED 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30156	NP_001260752.1	DnaJ	96..157	CDD:278647	20/61 (33%)
CG30156	NP_001260752.1	DUF1977	237..334	CDD:286411	23/113 (20%)
dnj-27	NP_001040704.1	DnaJ	18..>150	CDD:223560	39/186 (21%)
		DnaJ	20..82	CDD:278647	20/61 (33%)
		PDI_a_ERdj5_N	116..214	CDD:239301	24/124 (19%)
		Thioredoxin_like	222..>312	CDD:294274	5/15 (33%)
		ER_PDI_fam	438..750	CDD:273457
		PDI_a_ERdj5_C	438..543	CDD:239302
		PDI_a_ERdj5_C	549..664	CDD:239302
		PDI_a_ERdj5_C	670..773	CDD:239302
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910