Protein Alignment Serpina1 and Spn42Dd

DIOPT Version :10

• Sequence 1: NP_001421270.1
• Gene: Serpina1 / 24648
• RGDID: 3326
• Length: 411
• Species: Rattus norvegicus
• Sequence 2: NP_001163067.1
• Gene: Spn42Dd / 49808
• FlyBaseID: FBgn0028988
• Length: 372
• Species: Drosophila melanogaster
• Alignment Length: 365
• Identity: 113/365 - (30%)
• Similarity: 183/365 - (50%)
• Gaps: 28/365 - (7%)

  Rat    58 ELVHQSNTS-NIFFSPMSITTAFAMLSLGSKGDTRKQILEGLEFNLTQIPEAD---IHKAFHHLL 118
            :|:.:|:|: |:..||:||.|..:|:.:|::|.|.|::...|     .:|..|   :...:..||
  Fly    23 QLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSAL-----GLPSEDKEAVAARYGALL 82

  Rat   119 QTLNRPDSELQLNTGNGLFVNKNLKLVEKFLEEVKNNYHSEAFSVNFADSEEAKKVINDYVEKGT 183
            ..|...:....|...|.::||....|.:.:...|:..:.|||.|::..:...|.:.||.:|...|
  Fly    83 NDLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTNGPVAAERINQWVLDQT 147

  Rat   184 QGKIVDLMK--QLDEDTVFALVNYIFFKGKWKRPFNPEHTRDADFHVDKSTTVKVPMMNRLGMFD 246
            .|||..::.  .:..|....|||.|:|||:|:..|:|..||.:.|.|..:.:|.|.||.::|.|.
  Fly   148 SGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTANKSVPVQMMAQMGTFR 212

  Rat   247 MHYCSTLSSWVLMMDYLGN--ATAIFLLPDDGKMQHLEQTL---TKDLISRFLLNRQTRSAILYF 306
            .:|...|.:.|:.:.||.:  :..|||..:...:..||:.:   .:.|::        :...|..
  Fly   213 ANYFRDLDAQVIELPYLNSNLSMTIFLPREVEGLSALEEKIVGFARPLVA--------KEVYLKL 269

  Rat   307 PKLSISGTYNLKTLLSSLGITRVFNNDADLSGITED-APLKLSQAVHKAVLTLDERGTEAAGATV 370
            ||..|.....||..|..|||..:|.:.:||||:..| :..|:||..|||.|.::|.|.||||||.
  Fly   270 PKFKIEFRDELKETLEKLGIRELFTDKSDLSGLFADKSGGKVSQVSHKAFLEVNEEGAEAAGATS 334

  Rat   371 VEAVPMS-LPPQVKFDHPFIFMIVESETQSPLFVGKVIDP 409
            |.....: ....:..||||.|:|.::.|  ..|.|:|:.|
  Fly   335 VAVTNRAGFSTFLMADHPFAFVIRDANT--IYFQGRVVSP 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Serpina1	NP_001421270.1	serpinA1_A1AT	44..411	CDD:381012	113/365 (31%)
		RCL	367..386		4/19 (21%)
Spn42Dd	NP_001163067.1	serpin42Dd-like_insects	12..372	CDD:381070	112/363 (31%)