DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30095 and NLGN3

DIOPT Version :9

Sequence 1:	NP_725529.1	Gene:	CG30095 / 246453	FlyBaseID:	FBgn0050095	Length:	214	Species:	Drosophila melanogaster
Sequence 2:	NP_851820.1	Gene:	NLGN3 / 54413	HGNCID:	14289	Length:	848	Species:	Homo sapiens

Alignment Length:	150	Identity:	31/150 - (20%)
Similarity:	52/150 - (34%)	Gaps:	48/150 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 AAKGKWP--YVPGFMKYRVDNAARSFFNQNDSFIKQFCTKWIQVKE-------------CFRPLF 127
            :|...|.  |.|  :||....|.:...|..|:.....|.:....||             .|.|:.
Human   316 SALSSWAVNYQP--VKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVI 378

  Fly   128 DKS---NNTDVEVETLDAKIQGQRCNCDKLL--------------LSTEPPVPVVYFD---KNYI 172
            |..   ::.::.:|      ||:..|.|.:|              :..|..|....||   .|::
Human   379 DGDVIPDDPEILME------QGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFV 437

  Fly   173 GNV-----SSETILNTIEFL 187
            .|:     ..:|:..||:|:
Human   438 DNLYGYPEGKDTLRETIKFM 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30095	NP_725529.1	None
NLGN3	NP_851820.1	COesterase	36..624	CDD:278561	31/149 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	170..195
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	645..694
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900