DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30095 and Nlgn2

DIOPT Version :9

Sequence 1:	NP_725529.1	Gene:	CG30095 / 246453	FlyBaseID:	FBgn0050095	Length:	214	Species:	Drosophila melanogaster
Sequence 2:	NP_001351066.1	Gene:	Nlgn2 / 216856	MGIID:	2681835	Length:	836	Species:	Mus musculus

Alignment Length:	147	Identity:	32/147 - (21%)
Similarity:	52/147 - (35%)	Gaps:	44/147 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 AKGKWP--YVPGFMKYRVDNAARSFFNQNDSFIKQFCTKWIQVKECFRPLFDKSNN--------- 132
            |...|.  |.|  :||....||:...::.||.....|.:    ::..|.|.|:...
Mouse   294 AISSWSVNYQP--LKYTRLLAAKVGCDREDSTEAVECLR----RKSSRELVDQDVQPARYHIAFG 352

  Fly   133 --TDVEVETLDAKI---QGQRCNCDKLL--------------LSTEPPVPVVYFD---KNYIGNV 175
              .|.:|...|.:|   ||:..|.|.|:              ..:|..|....||   .|::.|:
Mouse   353 PVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSAESEDGVSASAFDFTVSNFVDNL 417

  Fly   176 -----SSETILNTIEFL 187
                 ..:.:..||:|:
Mouse   418 YGYPEGKDVLRETIKFM 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30095	NP_725529.1	None
Nlgn2	NP_001351066.1	COesterase	42..601	CDD:306613	32/147 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	623..661
		Required for interaction with LHFPL4. /evidence=ECO:0000269\|PubMed:28279354	679..699
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	711..735
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	791..836
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900