DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30095 and Ces1d

DIOPT Version :9

Sequence 1:	NP_725529.1	Gene:	CG30095 / 246453	FlyBaseID:	FBgn0050095	Length:	214	Species:	Drosophila melanogaster
Sequence 2:	NP_444430.2	Gene:	Ces1d / 104158	MGIID:	2148202	Length:	565	Species:	Mus musculus

Alignment Length:	208	Identity:	40/208 - (19%)
Similarity:	72/208 - (34%)	Gaps:	57/208 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LRRKIALHILPLFLAIFLFTMG------EAY--LKSVRVDEI--PFAGRKALANRRSSGIHLISS 57
            ||:|....:|...|.:.||.:.      |:|  |.:| :|.:  |.|..:.||.:..|
Mouse   285 LRQKTEDELLETSLKLNLFKLDLLGNPKESYPFLPTV-IDGVVLPKAPEEILAEKSFS------- 341

  Fly    58 LEHQRTFLHLFHVPYIICFYAAKGKWPYVPGFMKYRVDNAARSFFNQNDSFIKQFCTKWIQVKEC 122
                       .||||:.....:..| .:|..|.|.:..........|....|.:.|  :::.|.
Mouse   342 -----------TVPYIVGINKQEFGW-IIPTLMGYPLAEGKLDQKTANSLLWKSYPT--LKISEN 392

  Fly   123 FRPLF---------DKSNNTDVEVETLDAKIQGQRCNCDKLLLSTEPPVPVVYFDKNYIGNVSSE 178
            ..|:.         |.:...|:..:.:...:.|               ||.|...::: .:..:.
Mouse   393 MIPVVAEKYLGGTDDLTKKKDLFQDLMADVVFG---------------VPSVIVSRSH-RDAGAS 441

  Fly   179 TILNTIEFLESFL 191
            |.:...|:..||:
Mouse   442 TYMYEFEYRPSFV 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30095	NP_725529.1	None
Ces1d	NP_444430.2	COesterase	24..545	CDD:278561	40/208 (19%)
		Aes	<121..>239	CDD:223730
		Prevents secretion from ER. /evidence=ECO:0000255	562..565
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900