Protein Alignment CG30091 and TMPRSS13

DIOPT Version :10

• Sequence 1: NP_725484.1
• Gene: CG30091 / 246449
• FlyBaseID: FBgn0050091
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001070731.1
• Gene: TMPRSS13 / 84000
• HGNCID: 29808
• Length: 567
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 85/272 - (31%)
• Similarity: 126/272 - (46%)
• Gaps: 43/272 - (15%)

  Fly    27 CGVPMQLIPKIVGGVDAGELKNPWMALIKTNDEFICGGSVITNKFVLTAAHCMCTDEECIVKYTQ 91
            ||: ..:..:||||..|.:.|.||...:......||||::|..::|||||||.....|.:::..:
Human   317 CGL-RAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWK 380

  Fly    92 LTVTLGVYHLLATGEHNHPHEIYNVERVYIHDSFAIQNYRNDIALLRLQKSIVYKPQIKPLCILL 156
              |..|..:|     |..| |..::..:.|:.::..:....||||:||.|.:.....|.|.|:.:
Human   381 --VYAGTSNL-----HQLP-EAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPM 437

  Fly   157 NDQLKPQTDLIQEFTAI-GWGVT--GNGKMSNNLQMVKIYRIDRKMCEAAFWY-TFDYP-MFCAG 216
            :.    ||..:.|...| |:|.|  .:.|.|..|:.|::..||.|.|.....| ::..| |.|||
Human   438 HG----QTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAG 498

  Fly   217 -TAVGRDTCKRDSGGPLYIHMLFDGIKRATQLGIVSTGTEDC---RGFGMYTDVMGHIDFIERIV 277
             ...|||:|:.||||||    :.:...|....|:.|.|| .|   ...|:||.|
Human   499 DLRGGRDSCQGDSGGPL----VCEQNNRWYLAGVTSWGT-GCGQRNKPGVYTKV----------- 547

  Fly   278 LDADIEVVLPYI 289
                 ..|||:|
Human   548 -----TEVLPWI 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30091	NP_725484.1	Tryp_SPc	36..273	CDD:214473	79/245 (32%)
		Tryp_SPc	332..520	CDD:473915
TMPRSS13	NP_001070731.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..115
		PHA03378	<9..148	CDD:223065
		13 X 5 AA repeats of A-S-P-A-[GLQR]	9..93
		4 X 5 AA repeats of T-P-P-G-R	14..68
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	131..157
		SRCR_2	231..321	CDD:464747	2/4 (50%)
		Tryp_SPc	325..554	CDD:214473	82/261 (31%)