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Protein Alignment CG30091 and TMPRSS4

DIOPT Version :10

Sequence 1:	NP_725484.1	Gene:	CG30091 / 246449	FlyBaseID:	FBgn0050091	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	XP_005271670.1	Gene:	TMPRSS4 / 56649	HGNCID:	11878	Length:	494	Species:	Homo sapiens

Alignment Length:	279	Identity:	85/279 - (30%)
Similarity:	129/279 - (46%)	Gaps:	57/279 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 CGVPMQLIPKIVGGVDAGELKNPWMALIKTNDEFICGGSVITNKFVLTAAHCMCTDEECIVKYTQ 91
            ||..:: .|::||..:|.....||...|:.:.:.:||||::...:||||||       |..|:|.
Human   196 CGKSLK-TPRVVGVEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAH-------CFRKHTD 252

  Fly    92 L--------TVTLGVYHLLATGEHNHPHEIYNVERVYIHDSFAIQNYRNDIALLRLQKSIVYKPQ 148
            :        :..||.:..||            |.::.|.:...:....|||||::||..:.:...
Human   253 VFNWKVRAGSDKLGSFPSLA------------VAKIIIIEFNPMYPKDNDIALMKLQFPLTFSGT 305

  Fly   149 IKPLCI-LLNDQLKPQTDLIQEFTAIGWGVT--GNGKMSNNLQMVKIYRIDRKMCEA--AFWYTF 208
            ::|:|: ..:::|.|.|.|    ..||||.|  ..||||:.|....:..||...|.|  |:....
Human   306 VRPICLPFFDEELTPATPL----WIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADDAYQGEV 366

  Fly   209 DYPMFCAGTAVGR-DTCKRDSGGPLYI-----HMLFDGIKRATQLGIVSTGTEDCRG---FGMYT 264
            ...|.|||...|. |||:.||||||..     |:          :||||.| ..|.|   .|:||
Human   367 TEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQWHV----------VGIVSWG-YGCGGPSTPGVYT 420

  Fly   265 DVMGHIDFIERIVLDADIE 283
            .|..::::|..:..|..|:
Human   421 KVSAYLNWIYNVWKDRTIQ 439

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.