Protein Alignment CG30091 and Cfd

DIOPT Version :10

• Sequence 1: NP_725484.1
• Gene: CG30091 / 246449
• FlyBaseID: FBgn0050091
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001071110.1
• Gene: Cfd / 54249
• RGDID: 2498
• Length: 263
• Species: Rattus norvegicus
• Alignment Length: 258
• Identity: 76/258 - (29%)
• Similarity: 132/258 - (51%)
• Gaps: 32/258 - (12%)

  Fly    36 KIVGGVDAGELKNPWMALIKTNDEFICGGSVITNKFVLTAAHCMCTDEECIVKYTQLTVTLGVYH 100
            :|:||.:|.....|:||.::.|...:|||:::..::||:|||||    :.:.|...:.|.||.:.
  Rat    25 RILGGQEAMAHARPYMASVQVNGTHVCGGTLVDEQWVLSAAHCM----DGVTKDEVVQVLLGAHS 85

  Fly   101 LLATGEHNHPHEIYNVERVYIHDSFAIQNYRNDIALLRLQKSIVYKPQIKPLCILLND-QLKPQT 164
            |.:...:.|   :|:|:.|.:|......:..:|:.|.:|..:....|.::||.:...| ::||.|
  Rat    86 LSSPEPYKH---LYDVQSVVLHPGSRPDSVEDDLMLFKLSHNASLGPHVRPLPLQREDREVKPGT 147

  Fly   165 --DLIQEFTAIGWG-VTGNGKMSNNLQMVKIYRIDRKMCEAAFWY--TFDYPMFCAGTAVGRDTC 224
              |:      .||| ||..|:..:.||.:.:..:||..|....::  .....|.|| .:..||||
  Rat   148 LCDV------AGWGVVTHAGRRPDVLQQLTVSIMDRNTCNLRTYHDGAITKNMMCA-ESNRRDTC 205

  Fly   225 KRDSGGPLYIHMLFDGIKRATQLGIVSTGTEDC---RGFGMYTDVMGHIDFIERIVLDADIEV 284
            :.||||||   :..|.::     .:|:.|:..|   |..|::|.|..::.:||. ||..::.|
  Rat   206 RGDSGGPL---VCGDAVE-----AVVTWGSRVCGNRRKPGVFTRVATYVPWIEN-VLSGNVSV 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30091	NP_725484.1	Tryp_SPc	36..273	CDD:214473	71/245 (29%)
		Tryp_SPc	332..520	CDD:473915
Cfd	NP_001071110.1	Tryp_SPc	26..252	CDD:238113	73/248 (29%)
		Self-inhibitor loop. /evidence=ECO:0000250|UniProtKB:P00746	224..228		1/3 (33%)