Protein Alignment CG30091 and ACR

DIOPT Version :10

• Sequence 1: NP_725484.1
• Gene: CG30091 / 246449
• FlyBaseID: FBgn0050091
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001088.2
• Gene: ACR / 49
• HGNCID: 126
• Length: 421
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 80/275 - (29%)
• Similarity: 120/275 - (43%)
• Gaps: 40/275 - (14%)

  Fly    24 DEDCGVPMQLIP----KIVGGVDAGELKNPWMALIK-----TNDEFICGGSVITNKFVLTAAHCM 79
            |..||:..:..|    :||||..|.....|||..::     ::....||||::.:::|||||||.
Human    26 DGPCGLRFRQNPQGGVRIVGGKAAQHGAWPWMVSLQIFTYNSHRYHTCGGSLLNSRWVLTAAHCF 90

  Fly    80 C---TDEECIVKYTQLTVTLGVYHLLATGEHNHP-----HEIYNVERVYIHDSFAIQNYRNDIAL 136
            .   ...:..:.:....:|.|         :|.|     .|.| ||::.||:.:......|||||
Human    91 VGKNNVHDWRLVFGAKEITYG---------NNKPVKAPLQERY-VEKIIIHEKYNSATEGNDIAL 145

  Fly   137 LRLQKSIVYKPQIKPLCILLNDQLKPQTDLIQEFTAIGWGVTGN--GKMSNNLQMVKIYRIDRKM 199
            :.:...|.....|.|.|:.......|:..  |.....|||....  .:.|:.|...::..||..:
Human   146 VEITPPISCGRFIGPGCLPHFKAGLPRGS--QSCWVAGWGYIEEKAPRPSSILMEARVDLIDLDL 208

  Fly   200 CEAAFWYT--FDYPMFCAGTAVGR-DTCKRDSGGPLYIHMLFDGIKRA-TQLGIVSTGTEDCRGF 260
            |.:..||.  ......|||..||: |||:.||||||   |..|..:.| ..:||.|.|....|..
Human   209 CNSTQWYNGRVQPTNVCAGYPVGKIDTCQGDSGGPL---MCKDSKESAYVVVGITSWGVGCARAK 270

  Fly   261 --GMYTDVMGHIDFI 273
              |:||....::::|
Human   271 RPGIYTATWPYLNWI 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30091	NP_725484.1	Tryp_SPc	36..273	CDD:214473	75/257 (29%)
		Tryp_SPc	332..520	CDD:473915
ACR	NP_001088.2	Tryp_SPc	42..285	CDD:214473	75/257 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..316
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..383
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	397..421