DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30091 and SPE

DIOPT Version :9

Sequence 1:	NP_725484.1	Gene:	CG30091 / 246449	FlyBaseID:	FBgn0050091	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_651168.1	Gene:	SPE / 42791	FlyBaseID:	FBgn0039102	Length:	400	Species:	Drosophila melanogaster

Alignment Length:	287	Identity:	81/287 - (28%)
Similarity:	128/287 - (44%)	Gaps:	55/287 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 CGVPMQLIPKIVGGVDAGELKNPWMALIKTND------EFICGGSVITNKFVLTAAHCMCTDEEC 85
            ||  .....:|.||.:....:.|||.|::...      .|.|||:::.:::||||.||:.:.|
  Fly   127 CG--FLFADRIFGGTNTTLWEFPWMVLLQYKKLFSETYTFNCGGALLNSRYVLTAGHCLASRE-- 187

  Fly    86 IVKYTQLTVTLGVYHLLATGE---HNHP---------------HEIYNVERVYIHDSFAIQ--NY 130
                  |..:..|.|.:..||   ...|               |....||:..||:.:|..  :.
  Fly   188 ------LDKSGAVLHSVRLGEWDTRTDPDCTTQMNGQRICAPKHIDIEVEKGIIHEMYAPNSVDQ 246

  Fly   131 RNDIALLRLQKSIVYKPQIKPLCILLNDQLKPQTDLIQE------FTAIGWGVTGNGKMSNNLQM 189
            ||||||:||::.:.|...::|:|:       |...|:|.      ....|||:|.|.:.|.....
  Fly   247 RNDIALVRLKRIVSYTDYVRPICL-------PTDGLVQNNFVDYGMDVAGWGLTENMQPSAIKLK 304

  Fly   190 VKIYRIDRKMCE---AAFWYTFDYPMFCAGTAVGRDTCKRDSGGPLYIHMLFDGIKRATQLGIVS 251
            :.:...:...|:   ::|....|....|||..:|.|||..||||||.:.:...|.......|:.|
  Fly   305 ITVNVWNLTSCQEKYSSFKVKLDDSQMCAGGQLGVDTCGGDSGGPLMVPISTGGRDVFYIAGVTS 369

  Fly   252 TGTEDC--RGF-GMYTDVMGHIDFIER 275
            .||:.|  :|: |:||.....||:|::
  Fly   370 YGTKPCGLKGWPGVYTRTGAFIDWIKQ 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30091	NP_725484.1	Tryp_SPc	36..273	CDD:214473	78/274 (28%)
		Tryp_SPc	37..276	CDD:238113	79/277 (29%)
		Trypsin	310..520	CDD:278516
		Tryp_SPc	313..520	CDD:304450
SPE	NP_651168.1	CLIP	42..94	CDD:314844
SPE	NP_651168.1	Tryp_SPc	135..397	CDD:238113	79/277 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463562
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940