DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30091 and CG9649

DIOPT Version :9

Sequence 1:	NP_725484.1	Gene:	CG30091 / 246449	FlyBaseID:	FBgn0050091	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_650343.1	Gene:	CG9649 / 41727	FlyBaseID:	FBgn0038211	Length:	504	Species:	Drosophila melanogaster

Alignment Length:	273	Identity:	79/273 - (28%)
Similarity:	111/273 - (40%)	Gaps:	63/273 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 PKIVGGVDAGELKNPWMAL----IKTNDEFICGGSVITNKFVLTAAHCM------CTDEECIVKY 89
            |.|..|::....:.||||.    :..:..|:|||::|:.:.|::||||.      ...|..||..
  Fly   255 PFIHNGIEVERGQLPWMAALFEHVGRDYNFLCGGTLISARTVISAAHCFRFGSRNLPGERTIVSL 319

  Fly    90 TQLTV-------TLGVYHLLATGEHNHPHEIYNVERVYIHDSFAIQNYRNDIALLRLQKSIVYKP 147
            .:.::       ||||..||.       ||.|| ..||. |:        |:|||:|...:....
  Fly   320 GRNSLDLFSSGATLGVARLLI-------HEQYN-PNVYT-DA--------DLALLQLSNHVDIGD 367

  Fly   148 QIKPLCILLNDQLKPQTDLIQEFTAIGWGVTGNGKMSNNL-QMVKIYRIDRKMC------EAAFW 205
            .|||:| |.|:....:.....:....|||....|..:..| :|.....|.:..|      |.|.:
  Fly   368 YIKPIC-LWNENFLLELPSGHKSYVAGWGEDEKGNRNTRLAKMTDTDIITQWECRGNLSEENAKF 431

  Fly   206 YTFDYPMFCAGTAVGRDTCKRDSGGPLY-----IHMLFDGIKRATQLGIVSTG---TEDCRGF-- 260
            .|..  ..||..|.....|..||||.|.     |.||         .|:||.|   |..|...
  Fly   432 ITSH--TICASNAQASGPCSGDSGGGLMLQEQDIWML---------RGVVSAGQRMTNRCNLTLP 485

  Fly   261 GMYTDVMGHIDFI 273
            .:||||..||:::
  Fly   486 VIYTDVAKHIEWL 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30091	NP_725484.1	Tryp_SPc	36..273	CDD:214473	78/270 (29%)
		Tryp_SPc	37..276	CDD:238113	78/271 (29%)
		Trypsin	310..520	CDD:278516
		Tryp_SPc	313..520	CDD:304450
CG9649	NP_650343.1	GD_N	29..124	CDD:292649
		Tryp_SPc	257..498	CDD:238113	78/269 (29%)
		Tryp_SPc	259..497	CDD:214473	77/266 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436605
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm50645
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940