DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30091 and CG13318

DIOPT Version :9

Sequence 1:	NP_725484.1	Gene:	CG30091 / 246449	FlyBaseID:	FBgn0050091	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_649831.1	Gene:	CG13318 / 41048	FlyBaseID:	FBgn0037627	Length:	405	Species:	Drosophila melanogaster

Alignment Length:	249	Identity:	68/249 - (27%)
Similarity:	104/249 - (41%)	Gaps:	46/249 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 PWM-ALIKTNDEFICGGSVITNKFVLTAAHCMCTDEECIVKYTQLTVTLGVYHLLATGEHNHPHE 112
            ||. ||:.|.|.::.||::||.:.||||||.:..     :..|...|.||.:...:|.|.....:
  Fly   175 PWQAALLTTADVYLGGGALITAQHVLTAAHKVYN-----LGLTYFKVRLGEWDAASTSEPIPAQD 234

  Fly   113 IYNVERVYIHDSFAIQNYRNDIALLRLQK--SIVYKPQIKPLCILLNDQLKPQTDLI-QEFTAIG 174
            :| :..||::.||...|.:||:|:|:|..  |:..|..:..:|:       |.|..: |.....|
  Fly   235 VY-ISNVYVNPSFNPNNLQNDVAILKLSTPVSLTSKSTVGTVCL-------PTTSFVGQRCWVAG 291

  Fly   175 WGVT---GNGKMSNNLQMVKIYRIDRKMCEAAFWYT--------FDYPMFCAGTAVGRDTCKRDS 228
            ||..   ..|......:.|.:..|....|:||...|        ......|||...|:|.|..|.
  Fly   292 WGKNDFGATGAYQAIERQVDVPLIPNANCQAALQATRLGSSFVLSPTSFICAGGEAGKDACTGDG 356

  Fly   229 GGPL--------YIHMLFDGIKRATQLGIVSTGTEDCRGFGMYTDVMGHIDFIE 274
            |.||        |:..|.     |..:|....|..     |:|.:|..::.:|:
  Fly   357 GSPLVCTSNGVWYVVGLV-----AWGIGCAQAGVP-----GVYVNVGTYLPWIQ 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30091	NP_725484.1	Tryp_SPc	36..273	CDD:214473	67/246 (27%)
		Tryp_SPc	37..276	CDD:238113	68/249 (27%)
		Trypsin	310..520	CDD:278516
		Tryp_SPc	313..520	CDD:304450
CG13318	NP_649831.1	Tryp_SPc	169..402	CDD:238113	68/249 (27%)
CG13318	NP_649831.1	Tryp_SPc	169..399	CDD:214473	67/246 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45435543
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940