DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30091 and CG14088

DIOPT Version :9

Sequence 1:	NP_725484.1	Gene:	CG30091 / 246449	FlyBaseID:	FBgn0050091	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_649100.2	Gene:	CG14088 / 40098	FlyBaseID:	FBgn0036858	Length:	289	Species:	Drosophila melanogaster

Alignment Length:	273	Identity:	64/273 - (23%)
Similarity:	118/273 - (43%)	Gaps:	41/273 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 AGRGSARLLDEDCGVPMQ-LIPKIVGGVDAGELKNPWMALIKTNDEFICGGSVITNKFVLTAAHC 78
            :|.|||:.|...||.... |.|.|||         ||.|::......:..|::|..:|:||..|
  Fly    19 SGTGSAQFLGNICGERRDGLSPDIVG---------PWTAILHHFGRIVGVGTLIHERFILTDVH- 73

  Fly    79 MCTDEECIVK-----YTQLTVTLGVYHLLATGEHNHPHEIYNVERVYIHDSFAIQNYRNDIALLR 138
             |.|...:::     |.::...|...|::|.              .:.:.:|..:...|::.|::
  Fly    74 -CGDSIGVIRARLGEYGRIGSELAEDHIVAA--------------FFSNANFNPETQANNMGLMK 123

  Fly   139 LQKSIVYKPQIKPLCILLNDQLKPQTDLIQEFTAIGWGVTGNGKMSNNLQMVKIYRIDRKMCEAA 203
            |.:::|||..|.|:|||::.:::...|.:..|....|..:....|..:..::::.:...|:
  Fly   124 LLRTVVYKEHIIPVCILMDSRMQTFADELDYFNGTTWKNSDKSPMLRSKTVIRMPQACGKL---- 184

  Fly   204 FWYTFDYPMFCAGTAVGRDTCKRDSGGPLYIHMLFDGIKRATQLGIVSTGTEDCRGFGMYTDVMG 268
                 |:..||||.. ..|:|...||..|...:.:.|..|....||.::....|.....||||:.
  Fly   185 -----DHGQFCAGHK-DLDSCDEPSGAALTREIDYIGPNRTVLFGIANSVEVKCSNSRTYTDVVQ 243

  Fly   269 HIDFIERIVLDAD 281
            ...:|..::..::
  Fly   244 LHQWISMVIYSSN 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30091	NP_725484.1	Tryp_SPc	36..273	CDD:214473	54/241 (22%)
		Tryp_SPc	37..276	CDD:238113	55/243 (23%)
		Trypsin	310..520	CDD:278516
		Tryp_SPc	313..520	CDD:304450
CG14088	NP_649100.2	Tryp_SPc	42..251	CDD:304450	55/243 (23%)
CG14088	NP_649100.2	Tryp_SPc	42..248	CDD:214473	54/240 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.010