DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30091 and CG7542

DIOPT Version :9

Sequence 1:	NP_725484.1	Gene:	CG30091 / 246449	FlyBaseID:	FBgn0050091	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_001287099.1	Gene:	CG7542 / 39960	FlyBaseID:	FBgn0036738	Length:	270	Species:	Drosophila melanogaster

Alignment Length:	265	Identity:	72/265 - (27%)
Similarity:	121/265 - (45%)	Gaps:	26/265 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 LLDEDC-GVPM--QLIPKIVGGVDAGELKNPWMALIKT---NDEFICGGSVITNKFVLTAAHCMC 80
            ||...| .||:  .:.|.|..|..|...:.|:.|.:..   |....|||::|::.:::||||||.
  Fly     9 LLVGSCTAVPLLTDVEPYITNGEPAEVGQFPYQAGLNVSFGNWSTWCGGTLISHYWIITAAHCMD 73

  Fly    81 TDEECIVKYTQLTVTLGVYHLLATGEHNHPHEIYNVERVYIHDSFAIQNYRNDIALLRLQKSIVY 145
            ..|       .:||.||..::....|......:.....:.:|.::......|||:|:||...:.:
  Fly    74 GAE-------SVTVYLGAINIGDESEEGQERIMVEKSGIIVHSNYMASTVVNDISLIRLPAFVGF 131

  Fly   146 KPQIKPLCI--LLNDQLKPQTDLIQEFTAIGWG--VTGNGKMSNNLQMVKIYRIDRKMCEAAFWY 206
            ..:|:...:  .||.|. |..:.|:.| |.|||  ...:..:|..|:.|::..:...:|...:..
  Fly   132 TDRIRAASLPRRLNGQF-PTYESIRAF-ASGWGRESDASDSVSPVLRYVEMPIMPHSLCRMYWSG 194

  Fly   207 TFDYPMFCAGTAVGRDTCKRDSGGPLYIHMLFDGIKRATQLGIVSTGTE-DCR-GF-GMYTDVMG 268
            .....|.|..|..|:.||..||||||    ::.....:..:|..|.||. .|: || .::|.:..
  Fly   195 AVSEKMICMSTTSGKSTCHGDSGGPL----VYKQGNSSYLIGSTSFGTSMGCQVGFPAVFTRISS 255

  Fly   269 HIDFI 273
            ::|:|
  Fly   256 YLDWI 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30091	NP_725484.1	Tryp_SPc	36..273	CDD:214473	65/246 (26%)
		Tryp_SPc	37..276	CDD:238113	66/247 (27%)
		Trypsin	310..520	CDD:278516
		Tryp_SPc	313..520	CDD:304450
CG7542	NP_001287099.1	Tryp_SPc	27..263	CDD:238113	66/247 (27%)
CG7542	NP_001287099.1	Tryp_SPc	27..260	CDD:214473	65/245 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436341
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940