DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30091 and Hayan

DIOPT Version :9

Sequence 1:	NP_725484.1	Gene:	CG30091 / 246449	FlyBaseID:	FBgn0050091	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_001097020.1	Gene:	Hayan / 32831	FlyBaseID:	FBgn0030925	Length:	637	Species:	Drosophila melanogaster

Alignment Length:	276	Identity:	85/276 - (30%)
Similarity:	127/276 - (46%)	Gaps:	48/276 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 GVPMQLIPKIVGG--VDAGELKNPWMALIKTND----EFICGGSVITNKFVLTAAHCMCTDEECI 86
            |.|:.:  .|:.|  ||.|..  |.||.|..|.    .|.||||:|.::||||||||:.:|:.
  Fly   378 GKPLTV--HILDGERVDRGVY--PHMAAIAYNSFGSAAFRCGGSLIASRFVLTAAHCVNSDDS-- 436

  Fly    87 VKYTQLTVTLGVYHLLATGEHNHP-HEIYNVERVYIHDSFAIQNYRNDIALLRLQKSIVYKPQIK 150
               |...|.||..::    |:..| ::..||..|.||..::..:...|||:|:|.:.......|:
  Fly   437 ---TPSFVRLGALNI----ENPEPGYQDINVIDVQIHPDYSGSSKYYDIAILQLAEDAKESDVIR 494

  Fly   151 PLCILLNDQLKPQTDLIQEFTAIGWGVTG--NGKMSNNLQMVKIYRIDRKMCEAAFWYTFDYP-- 211
            |.| |..|:..|..:  .::...||||..  |..:|..|....:..:....|.|:|   .:.|
  Fly   495 PAC-LYTDRSDPPAN--YKYFVAGWGVMNVTNRAVSKILLRAALDLVPADECNASF---AEQPSA 553

  Fly   212 -----------MFCAGTAVGR-DTCKRDSGGPLYIHMLFDGIKRATQL-GIVSTGTEDC--RGFG 261
                       ..||.....| |.|:.||||||.:.:  |.:.....: |::|:|. .|  :..|
  Fly   554 NRTLRRGVIASQLCAADKNQRKDACQGDSGGPLILEI--DDVDGTYSIVGVISSGF-GCATKTPG 615

  Fly   262 MYTDVMGHIDFIERIV 277
            :||.|...:|:||.||
  Fly   616 LYTRVSSFLDYIEGIV 631

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30091	NP_725484.1	Tryp_SPc	36..273	CDD:214473	79/262 (30%)
		Tryp_SPc	37..276	CDD:238113	81/264 (31%)
		Trypsin	310..520	CDD:278516
		Tryp_SPc	313..520	CDD:304450
Hayan	NP_001097020.1	CLIP	32..80	CDD:197829
		Tryp_SPc	384..627	CDD:214473	79/262 (30%)
		Tryp_SPc	385..630	CDD:238113	81/264 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437501
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940