Protein Alignment CG30091 and HGFAC

DIOPT Version :10

• Sequence 1: NP_725484.1
• Gene: CG30091 / 246449
• FlyBaseID: FBgn0050091
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001284368.1
• Gene: HGFAC / 3083
• HGNCID: 4894
• Length: 662
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 77/271 - (28%)
• Similarity: 119/271 - (43%)
• Gaps: 56/271 - (20%)

  Fly    33 LIPKIVGGVDAGELKNPWMALIKTNDEFICGGSVITNKFVLTAAHCMC----TDEECIV------ 87
            |.|:|:||..:....:||:|.|...|.| |.||::...:|::||||..    .|...:|
Human   411 LRPRIIGGSSSLPGSHPWLAAIYIGDSF-CAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHFF 474

  Fly    88 -KYTQLTVTLGVYHLLATGEHNHPHEIYNVERVYIHDSFAIQNYRNDIALLRLQKS---IVYKPQ 148
             :.|.:|.|.|:       |...|:.:|:|.....|          |:.|:||:|.   ...:.|
Human   475 NRTTDVTQTFGI-------EKYIPYTLYSVFNPSDH----------DLVLIRLKKKGDRCATRSQ 522

  Fly   149 -IKPLCILLNDQLKPQTDLIQEFTAIGWG-----VTGNGKMSNNLQMVKIYRIDRKMCEAAFWYT 207
             ::|:|:.......|.....|   ..|||     |:|   .|::|:...:..:....|.:...|.
Human   523 FVQPICLPEPGSTFPAGHKCQ---IAGWGHLDENVSG---YSSSLREALVPLVADHKCSSPEVYG 581

  Fly   208 FDYP--MFCAG-TAVGRDTCKRDSGGPLYIHMLFDGIKRATQLGIVSTGTEDCRGF---GMYTDV 266
            .|..  |.||| .....|.|:.||||||....  :|:  |...||:|.| :.|...   |:||.|
Human   582 ADISPNMLCAGYFDCKSDACQGDSGGPLACEK--NGV--AYLYGIISWG-DGCGRLHKPGVYTRV 641

  Fly   267 MGHIDFI-ERI 276
            ..::|:| :||
Human   642 ANYVDWINDRI 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30091	NP_725484.1	Tryp_SPc	36..273	CDD:214473	72/262 (27%)
		Tryp_SPc	332..520	CDD:473915
HGFAC	NP_001284368.1	PRK14954	<32..>100	CDD:184918
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	64..102
		FN2	102..148	CDD:128373
		EGF_CA	162..197	CDD:238011
		FN1	200..240	CDD:238018
		EGF_CA	245..278	CDD:238011
		Kringle	286..367	CDD:395005
		Tryp_SPc	415..650	CDD:238113	73/263 (28%)