DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30091 and CG33458

DIOPT Version :9

Sequence 1:	NP_725484.1	Gene:	CG30091 / 246449	FlyBaseID:	FBgn0050091	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_995854.2	Gene:	CG33458 / 2768846	FlyBaseID:	FBgn0053458	Length:	281	Species:	Drosophila melanogaster

Alignment Length:	285	Identity:	91/285 - (31%)
Similarity:	138/285 - (48%)	Gaps:	52/285 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 GSARLLDEDCGVPMQLIPKIVGGVDAGELKNPWMALIKTNDEFICGGSVITNKFVLTAAHCM--- 79
            |.:.||:.|||: .:...:|.||.|:..:.|||:|.:..|.:||||||::.:.||||||||.
  Fly    20 GYSYLLEWDCGI-SKYTYRITGGRDSPLMLNPWLAYLHINSKFICGGSLLNHWFVLTAAHCFRDK 83

  Fly    80 ------------------CTDEECIVKYTQLTVTLGVYHLLATGEHNHPHEIYNVERVYIHDSFA 126
                              |.:.||..                      ||..|.:.:..||..:.
  Fly    84 NAKVLVRLGENDASQKIDCNESECAA----------------------PHLEYMIMQKLIHPLYR 126

  Fly   127 IQNYRNDIALLRLQKSIVYKPQIKPLCILLNDQLKPQTDLIQEFTAIGWGVTGNGKMSNNLQMVK 191
            ..:| .||||.:|.:.:||...|:|:|::||...:...|.|:.|...|||.|...::|:.||:.:
  Fly   127 TAHY-YDIALAKLNRYVVYTDSIRPICLMLNPNWQVYVDTIRYFIITGWGATNASEVSDKLQLTR 190

  Fly   192 IYRIDRKMCEAAFWYTFDYPMFCAGTA---VGRDTCKRDSGGPLYIHMLFDGIKRATQLGIVSTG 253
            |.:|||..|...|.|..|....|||.:   ||    |.||||||...:.:...||..|.||||..
  Fly   191 IPQIDRFTCRYWFGYMVDRTHICAGESKHYVG----KGDSGGPLGSMVDYKYAKRFFQFGIVSHL 251

  Fly   254 TEDCRGFGMYTDVMGHIDFIERIVL 278
            .:...|..::|:::.:.::|.|.::
  Fly   252 RQPFHGVSVFTNILSYSNWIHRTII 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30091	NP_725484.1	Tryp_SPc	36..273	CDD:214473	83/260 (32%)
		Tryp_SPc	37..276	CDD:238113	84/262 (32%)
		Trypsin	310..520	CDD:278516
		Tryp_SPc	313..520	CDD:304450
CG33458	NP_995854.2	Tryp_SPc	37..271	CDD:214473	83/260 (32%)
CG33458	NP_995854.2	Tryp_SPc	38..274	CDD:238113	84/262 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BQ4K
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108863
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.710