DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30091 and CG30288

DIOPT Version :9

Sequence 1:	NP_725484.1	Gene:	CG30091 / 246449	FlyBaseID:	FBgn0050091	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_001097398.1	Gene:	CG30288 / 246531	FlyBaseID:	FBgn0050288	Length:	282	Species:	Drosophila melanogaster

Alignment Length:	275	Identity:	88/275 - (32%)
Similarity:	132/275 - (48%)	Gaps:	39/275 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 SARLLDEDCGVPMQ--LIPKIVGGVDAGELKNPWMALIKTNDEFICGGSVITNKFVLTAAHCMCT 81
            |.|||:.|||....  ...:|.||.|||...||||..:..:.:.:||||:||.:|||||.||:..
  Fly    23 SGRLLENDCGTTSSNGYRARIDGGRDAGMESNPWMVRVMISGKAVCGGSLITARFVLTAEHCISP 87

  Fly    82 DEECIVKYTQLTVTLGVYHLLATGEHNHPHEIY--------------NVERVYIHDSFAIQNYRN 132
                            :|..:..||::..|.|:              :|:|..:|     .|...
  Fly    88 ----------------MYMNVRLGEYDTRHPIFDCDDFVCTPRAYNVDVDRKIVH-----SNPGY 131

  Fly   133 DIALLRLQKSIVYKPQIKPLCILLNDQLKPQTDLIQEFTAIGWGVTGNGKMSNNLQMVKIYRIDR 197
            ||.|||:|:|:::...::|:|::|...|......|..|...|||...:|:..:.||...:.::.:
  Fly   132 DIGLLRMQRSVIFSNYVRPICLILGKTLGGNPLSILRFNFTGWGTNSDGEEQDRLQTATLQQLPQ 196

  Fly   198 KMCEAAFWYTFDYPMFCAGTAVGRDTCKRDSGGPLYIHMLFDGIKRATQLGIVSTGTEDCRGFGM 262
            ..||.. ....|....|||:.:. |:||.||||||.....|:|..|..|.|:.|.|...|.|.|:
  Fly   197 WSCERP-GRPLDISYICAGSYIS-DSCKGDSGGPLSAIRTFEGQGRVFQFGVASQGLRLCSGLGI 259

  Fly   263 YTDVMGHIDFIERIV 277
            ||:|....|:|..::
  Fly   260 YTNVTHFTDWILDVI 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30091	NP_725484.1	Tryp_SPc	36..273	CDD:214473	80/250 (32%)
		Tryp_SPc	37..276	CDD:238113	81/252 (32%)
		Trypsin	310..520	CDD:278516
		Tryp_SPc	313..520	CDD:304450
CG30288	NP_001097398.1	Tryp_SPc	42..270	CDD:214473	80/250 (32%)
CG30288	NP_001097398.1	Tryp_SPc	45..270	CDD:238113	79/247 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BQ4K
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108863
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.710