DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30091 and CG30090

DIOPT Version :9

Sequence 1:	NP_725484.1	Gene:	CG30091 / 246449	FlyBaseID:	FBgn0050091	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_725487.1	Gene:	CG30090 / 246448	FlyBaseID:	FBgn0050090	Length:	291	Species:	Drosophila melanogaster

Alignment Length:	266	Identity:	103/266 - (38%)
Similarity:	142/266 - (53%)	Gaps:	14/266 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 GSARLLDEDCGVPMQLIP-KIVGGVDAGELKNPWMALIKTNDEFICGGSVITNKFVLTAAHCMCT 81
            |:...|:..||:....|. ||:||.||....|||||.|.::.:.||||::||.:||||||||:
  Fly    20 GNGEYLEPRCGLTANTIAFKIIGGRDAIINSNPWMAYIHSSVKLICGGTLITQRFVLTAAHCV-- 82

  Fly    82 DEECIVKYTQLTVTLGVYHLLATGEHNH----PH-EIYNVERVYIHDSFAIQNYRNDIALLRLQK 141
            :|...||     |.||.|...||.:.|.    |. |.::|:..:.|..|:.....||||||||.|
  Fly    83 NEGSAVK-----VRLGEYDDTATEDCNSKICIPRAEEHDVDMAFRHGKFSEIKNLNDIALLRLAK 142

  Fly   142 SIVYKPQIKPLCILLNDQLKPQTDLIQEFTAIGWGVTGNGKMSNNLQMVKIYRIDRKMCEAAFWY 206
            .:.:|..|.|:||:|....:...|.|:.|.|.|||.|...:....||:.::.|.:...|..|...
  Fly   143 FVTFKAHISPICIILGTSKRELVDSIEWFVATGWGETRTHRTRGVLQITQLQRYNSSQCMQALGR 207

  Fly   207 TFDYPMFCAGTAVGRDTCKRDSGGPLYIHMLFDGIKRATQLGIVSTGTEDCRGFGMYTDVMGHID 271
            .......||| .:|.|||..||||||:..:......|..|.|:||.|:.:|.|.|:||||..:.|
  Fly   208 LVQQNQICAG-RLGSDTCNGDSGGPLFQTVRHMDKMRPVQFGVVSYGSRECSGIGVYTDVYSYAD 271

  Fly   272 FIERIV 277
            :|..:|
  Fly   272 WIATVV 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30091	NP_725484.1	Tryp_SPc	36..273	CDD:214473	96/241 (40%)
		Tryp_SPc	37..276	CDD:238113	96/243 (40%)
		Trypsin	310..520	CDD:278516
		Tryp_SPc	313..520	CDD:304450
CG30090	NP_725487.1	Tryp_SPc	39..273	CDD:214473	96/241 (40%)
CG30090	NP_725487.1	Tryp_SPc	40..276	CDD:238113	96/243 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463354
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	1	0.900	-	-		E33208_3BQ4K
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108863
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.740