Protein Alignment CG30091 and F11

DIOPT Version :10

• Sequence 1: NP_725484.1
• Gene: CG30091 / 246449
• FlyBaseID: FBgn0050091
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_005262878.1
• Gene: F11 / 2160
• HGNCID: 3529
• Length: 626
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 85/282 - (30%)
• Similarity: 132/282 - (46%)
• Gaps: 49/282 - (17%)

  Fly    16 GRG-----SARL--LDEDCGVPMQLIPKIVGGVDAGELKNPWMALIKT---NDEFICGGSVITNK 70
            |||     :.||  :|.:|...::  |:||||..:...:.||...:.|   ....:||||:|.|:
Human   363 GRGGISGYTLRLCKMDNECTTKIK--PRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQ 425

  Fly    71 FVLTAAHCMCTDEECIVKYTQLTVTLGVYH-LLATGEHNHPHEIYNVERVYIHDSFAIQNYRNDI 134
            ::||||||....|...:        |.||. :|...|.......:.|:.:.|||.:.:.....||
Human   426 WILTAAHCFYGVESPKI--------LRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDI 482

  Fly   135 ALLRLQKSIVYKPQIKPLCILLNDQLKPQTDLI-QEFTAIGWGVTG-NGKMSNNLQMVKIYRIDR 197
            |||:|:.::.|....:|:|:    ..|...::| .:....|||... ..|:.|.||..||..:..
Human   483 ALLKLETTVNYTDSQRPICL----PSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTN 543

  Fly   198 KMCEAAF-WYTFDYPMFCAG-TAVGRDTCKRDSGGPLYI------HMLFDGIKRATQLGIVSTGT 254
            :.|:..: .:...:.|.||| ...|:|.||.||||||..      |:          :||.|.|
Human   544 EECQKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHL----------VGITSWG- 597

  Fly   255 EDC---RGFGMYTDVMGHIDFI 273
            |.|   ...|:||:|:.::|:|
Human   598 EGCAQRERPGVYTNVVEYVDWI 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30091	NP_725484.1	Tryp_SPc	36..273	CDD:214473	76/253 (30%)
		Tryp_SPc	332..520	CDD:473915
F11	XP_005262878.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..375	CDD:128519	4/11 (36%)
		Tryp_SPc	389..619	CDD:238113	76/252 (30%)