Protein Alignment CG30091 and F10

DIOPT Version :10

• Sequence 1: NP_725484.1
• Gene: CG30091 / 246449
• FlyBaseID: FBgn0050091
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 82/261 - (31%)
• Similarity: 129/261 - (49%)
• Gaps: 47/261 - (18%)

  Fly    34 IPKIVGGVDAGELKNPWMA-LIKTNDEFICGGSVITNKFVLTAAHCMCTDEECIVKYTQLTVTLG 97
            :.:||||.:..:.:.||.| ||...:|..|||::::..::||||||:...:...|:
Human   232 LTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVR--------- 287

  Fly    98 VYHLLATGEHNHPHE-----IYNVERVYIHDSFAIQNYRNDIALLRLQKSIVYKPQIKPLCILLN 157
                  .|:.|...|     ::.||.|..|:.|..:.|..|||:|||:..|.::..:.|.|:
Human   288 ------VGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACL--- 343

  Fly   158 DQLKPQTD-----LIQEFTAI--GWGVT-GNGKMSNNLQMVKIYRIDRKMCEAAFWYTFDYPMFC 214
                |:.|     |:.:.|.|  |:|.| ..|:.|..|:|:::..:||..|:.:..:.....|||
Human   344 ----PERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFC 404

  Fly   215 AG-TAVGRDTCKRDSGGPLYIHML-FDGIKRATQLGIVSTGTEDC--RG-FGMYTDVMGHIDFIE 274
            || .....|.|:.|||||   |:. |......|  ||||.| |.|  :| :|:||.|...:.:|:
Human   405 AGYDTKQEDACQGDSGGP---HVTRFKDTYFVT--GIVSWG-EGCARKGKYGIYTKVTAFLKWID 463

  Fly   275 R 275
            |
Human   464 R 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30091	NP_725484.1	Tryp_SPc	36..273	CDD:214473	80/255 (31%)
		Tryp_SPc	332..520	CDD:473915
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203
		Tryp_SPc	235..464	CDD:238113	81/256 (32%)
		O-glycosylated at one site	476..485